Results 81 to 90 of about 8,006,158 (295)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

POS-469 ENHANCING PATIENT CARE BY PARTNERING WITH PATIENTS IN KIDNEY HEALTH RESEARCH

Kidney International Reports, 2021
L. Getchell, M. Beaucage, D. Hillier, A. MacPhee, H. Vorster, G. Pollock   +5 more
doaj   +1 more source

Relações interpessoais, equipe de trabalho e seus reflexos na atenção básica

Revista Brasileira de Educação Médica
A formação e afirmação de vínculos profissionais têm por finalidade o desenvolvimento de relações interpessoais em equipes de trabalho, compreendendo a sua realidade para promover o crescimento de cada um dos profissionais individualmente e do grupo de ...
Alexandra da Rosa Martins, Denise Bermudez Pereira, Maria Laura Silveira Nogueira Nogueira, Celeste dos Santos Pereira, Greice Schrader Schrader, Maira Buss Thoferhn   +5 more
doaj   +1 more source

Understanding Rural Patients’ Perspectives on Patient Care Teams

PRiMER
Introduction: With a critical primary care clinician shortage, team-based care (TBC) is under development to enhance access, especially in rural regions. However, there has been limited discussion about TBC from the patient’s perspective. We explored rural patient preferences for composition of their current and ideal primary health care team. Methods:
Amy, Tite, Brynn, Magner, Emily, Pierce, Mindy Ann, Smith   +3 more
openaire   +2 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Involvement of patients or their representatives in quality management functions in EU hospitals:implementation and impact on patient-centred care strategies [PDF]

, 2014
OBJECTIVE: The objective of this study was to describe the involvement of patients or their representatives in quality management (QM) functions and to assess associations between levels of involvement and the implementation of patient-centred care ...
Kristensen, S, Ommen, O, Pfaff, H, Bottaro, S., Kringos, D.S., Wang, A., Lívio, A., Shaw, C., Plochg, T, Kristensen, S., Depaigne-Loth, A., Depaigne-Loth, A, Kutaj-Wasikowska, H, Kus, H, Secanell, M., Mannion, Russell, Ozturk, K., Bruneau, Charles, Leite, I, Botje, D, Groene, Oliver, Kutryba, B, Saillour-Glenisson, F, Garel, Pascal, Almeman, F., Lívio, A, Eiras, M, Wang, A, Franca, M, Thompson, Caroline A., Saluvan, M, Hammer, A., Almeman, F, Bartels, Paul, Jones, S., Kringos, DS, Secanell, M, Groene, O., Garel, P, Dersarkissian, Maral, Groene, O, Sunol, R., Kutaj-Wąsikowska, Halina, Leite, I., Lopez, MA, Arah, OA, Botje, Daan, Suñol Sala, Rosa, Thompson, Caroline A, Wagner, C, Kus, H., Vlcek, Frantisek, Klazinga, N. S., Franca, M., Escoval, Ana, Sunol, R, Plochg, T., Jones, S, Thompson, A, Car, M., DUQuE Project Consortium, Klazinga, Niek S, Wang, Aolin, Lombarts, M.J.M.H., Escoval, A, Eiras, M., Wagner, Cordula, Bartels, P, Chow, A., Shaw, C, Arah, Onyebuchi A, DerSarkissian, M, ?, ?, Klazinga, N, Klaus, E, Arah, Onyebuchi A., Bruneau, C, Vallejo, P., Thompson, A., Kutryba, B., Lombarts, MJMH, Car, M, Sunol, Rosa, Vlcek, F, Ommen, O., Saluvan, M., Thompson, CA, Klaus, E., Bottaro, S, Thompson, Andrew, Saillour-Glenisson, F., Vallejo, P, Lopez, M. A., Klazinga, Niek S., Mannion, R, Michel, P, Arah, Onyebuchi A.., Ozturk, K, Pfaff, H., Universitat Autònoma de Barcelona, Hammer, A, Michel, P.   +101 more
core   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

3317 Translating simulation-based team leadership training into patient-centered outcomes

Journal of Clinical and Translational Science, 2019
OBJECTIVES/SPECIFIC AIMS: The objective of this research was to assess the clinical impact of simulation-based team leadership training on team leadership effectiveness and patient care during actual trauma resuscitations.
Rosemarie Fernandez, Elizabeth D. Rosenman, Anne K. Chipman, Sarah Brolliar, Marie C. Vrablik, Anthony T Misisco, Jeff Olenick, James Grand, Colleen Kalynych, Steve W. J. Kozlowski, Georgia T. Chao   +10 more
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source