Results 91 to 100 of about 6,821,110 (300)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Measuring the quality of patient-centered care: why patient-reported measures are critical to reliable assessment

, 2015
Flora Tzelepis, Robert W Sanson-Fisher, Alison C Zucca, Elizabeth A FradgleyPriority Research Centre for Health Behaviour, University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, AustraliaPurpose: The Institute of Medicine (IOM ...
Sanson-Fisher RW, Fradgley EA, Tzelepis F, Zucca AC   +3 more
core  

How culture influences patient preferences for patient-centered care with their doctors

, 2022
Background: Patient-centered care (PCC) is the prevailing model of care globally. However, most research on PCC has been conducted in Westernized countries or has focused on only two facets of PCC: decision-making and information exchange.
Eigeland, Jessica, Jones, L, Maria Benedetti, Jones, Liz, Pines, Rachyl, Sheeran, N, Blair Jin, Jessica Eigeland, Benedetti, M, Rachyl Pines, Eigeland, J, Liz Jones, Jin, Blair, Benedetti, Maria, Pamoso, A, Aron Pamoso, Sheeran, Nicola, Pamoso, Aron, Pines, R, Nicola Sheeran, Jin, B   +20 more
core   +1 more source

Facilitators and barriers of patient-centered care at the organizational-level: a study of three district hospitals in the central region of Ghana

BMC Health Services Research, 2019
Background Improving patient experience of care has gained enormous attention from policy makers and providers of healthcare services in Ghana. In spite of the supposed support for patient-centered care as the means for improving patient experience of ...
Jacqueline Nkrumah, Gordon Abekah-Nkrumah   +1 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

(Not) Being cared for in hospital settings: patients’ experience from Foucault’s perspective [PDF]

Revista Brasileira de Enfermagem
Objectives: to understand patients’ experience of (lack of) care in hospital settings from Foucault’s perspective. Methods: this is the partial result of research using Grounded Theory as a methodological framework, in light of Michel Foucault’s ...
Débora Thais Siqueira Soares, Maria Ribeiro Lacerda, Ana Paula Hermann   +2 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Evaluating the Patient Centered Primary Care Home initiative

, 2014
author/organization: Bill Wright, PhD, Grace Li, PhD, the Center for Outcomes Research & Education Providence Health & Services.Title from PDF title page (viewed on March 31, 2023).This archived document is maintained by the Oregon State Library as part ...

core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source