Results 61 to 70 of about 5,028,715 (249)

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

Advanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li, Mary Ann Go, Hualong Zhang, Robertas Aleksynas, Juliana Kim, Mingyang Gao, Seigfred Prado, Magdalena Sastre, Simon R. Schultz   +8 more
wiley   +1 more source

MANAGEMENT OF ACUTE PAIN IN PATIENT WITH PATIENT-CONTROLLED ANALGESIA

e-Jurnal Medika Udayana, 2013
Acute and chronic pain each has its own challenges because these patients are often dependent on opioids and have many psychosocial factors. None of these methods of pain control are superior than others.
Siska Permanasari Sinardja, IGN Mahaalit Aribawa   +1 more
doaj  

Regional anesthesia or patient-controlled analgesia and compartment syndrome in orthopedic surgical procedures: a systematic review

, 2016
Elizabeth BS Driscoll,1 Ana Hosseinzadeh Maleki,2 Leila Jahromi,3 Brittany Nelson Hermecz,4 Lauren E Nelson,5 Imelda L Vetter,6 Spencer Evenhuis,2 Lee Ann Riesenberg2 1Department of Anesthesiology, University of Tennessee, Knoxville, TN, 2Department of ...
Evenhuis S, Hermecz BN, Nelson LE, Driscoll EBS, Maleki AH, Vetter IL, Jahromi L, Riesenberg LA   +7 more
core  

PAin SoluTions in the Emergency Setting (PASTIES); A protocol for two open-label randomised trials of patient-controlled analgesia (PCA) versus routine care in the emergency department

, 2013
Introduction: Pain is the commonest reason that patients present to an emergency department (ED), but it is often not treated effectively. Patient controlled analgesia (PCA) is used in other hospital settings but there is little evidence to support its ...
Squire, Rosalyn, Pritchard, Colin, Smith, Jason E., Hayward, Christopher J., Creanor, Siobhan, Smith, Jason E, Ewings, Paul, Barton, Andy, Benger, Jonathan Richard, Hayward, Christopher J, Rockett, Mark, Benger, Jonathan   +11 more
core   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Patient-controlled analgesia in surgical patient [PDF]

, 2016
Günümüzde cerrahi tedavi yöntemleri ile ilgili gelişmelere karşın ameliyat sonrası ağrı, hastaların en sık yaşadığı sorunlardan biridir. Kontrol altına alınamayan ağrı, ameliyat sonrası dönemde iyileşme sürecini ve hastanede kalış süresini uzatan birçok ...
Çilingir, Dilek, Şahin, Ceyda Uzun
core   +1 more source

Analgesia pós-operatória: comparação entre cateter peridural e cateter na ferida operatória. [PDF]

, 2009
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Brunharo, Guilherme Muriano
core  

Effect of Combining Dexmedetomidine and Morphine for Intravenous Patient- Controlled Analgesia

, 2011
Background. Perioperative use of dexmedetomidine is associated with reduction in postoperative analgesic requirements. This study examined whether dexmedetomidine added to i.v.
林子富;葉育彰;林峰盛;王永彬;林珍榮;孫維仁;范守仁, LIN, TZU-FU;YEH, YU-CHANG;LIN, FENG-SHENG;WANG, YONG-PING;LIN, CHEN-JUNG;SUN, WEI-ZEN;FAN, SHOU-ZEN   +1 more
core   +1 more source

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

Advanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer, Noël Strasser, Ilakkiya Ravindrarajah, Elsa Wrenger, Kristian Ivkovic, Jan Ševčík, Sima Šarčević, Lenka Červenková, Jáchym Rosendorf, Václav Liška, Alexandre H. Anthis, Thomas Rduch, Inge K. Herrmann   +12 more
wiley   +1 more source