Results 181 to 190 of about 6,814,812 (297)

The development of a Patient Decision Aid and Patient Concerns Inventory for people diagnosed with recurrent head and neck cancer: a mixed-methods study protocol. [PDF]

BMJ Open
Georgopoulou S, Brady G, Fuller M, Thick M, Cruickshank S, Paleri V, Roe J.   +6 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Factors Influencing the Adoption of a Patient Decision Aid Development Platform: A Qualitative Study. [PDF]

MDM Policy Pract
Bélanger J, Bonner C, Bravo P, Dionne É, Hastings K, Légaré F, Prévost K, Selby K, Stacey D, Straus SE, Thombs BD, Giguere A.   +11 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

International patient decision aid standards (IPDAS) collaboration

, 2013
International Patient Decision Aid Standards (IPDAS)
core  

Effect of a patient decision aid on shared decision making in patients with differentiated thyroid cancer: a randomized controlled trial. [PDF]

Oncologist
Koot A, Ottevanger P, Hermens R, Aarts A, Walraven J, Bonenkamp H, de Wilt J, Nieuwenhuijzen G, van der Veen A, Keemers M, Zandee W, Blanken C, van Aken M, Donders R, Stalmeier P, Netea-Maier R, COMBO study group .   +16 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Development of a patient decision aid prototype on the decision to continue, reduce or discontinue antipsychotic medication following remission of first-episode psychosis. [PDF]

BJPsych Open
Béchard L, Corbeil O, Huot-Lavoie M, Roy O, Brodeur S, Bouchard E, Martel J, Pavey N, Achim AM, Menear M, Roy MA, Lauzier S, Demers MF.   +12 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Implementing an Asthma Patient Decision Aid in Primary Care: A Qualitative Study of Clinicians' and Patients' Perspectives on Its Sustainability. [PDF]

J Prim Care Community Health
Leow MQH, Zheng L, Lim YFC, Ngoh ASH, Gun SY, Tan NC.   +5 more
europepmc   +1 more source