Results 191 to 200 of about 6,814,812 (297)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Feasibility of a Patient Decision Aid for Advance Care Planning Among Adults With a History of Intensive Care Admission: A Pilot Randomized Trial. [PDF]

J Patient Exp
Yamamoto K.
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Effect of an in-consult patient decision aid on decisional quality and involvement for patients with severe hip or knee osteoarthritis: a multicenter, cluster randomized controlled trial. [PDF]

Acta Orthop
Pedersen TA, Lindberg-Larsen M, Jensen CM, Steffensen KD, Varnum C.   +4 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

The impact of a patient decision aid for patients with advanced laryngeal carcinoma - a multicenter study. [PDF]

BMC Med Inform Decis Mak
Heirman AN, Petersen JF, Al-Mamgani A, Eerenstein SEJ, de Kleijn BJ, Hoebers F, Tijink BM, van der Molen L, Halmos GB, Dirven R, Stuiver MM, van den Brekel MWM.   +11 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Updated International Patient Decision Aid Standards (IPDAS version 5.0): modified Delphi, evidence informed consensus process.

BMJ
Volk RJ, Lewis KB, Smith M, Carley M, Barry MJ, Bekker HL, Härter M, Hoffmann T, McCaffery K, Pignone M, Steffensen KD, Sepucha K, Thompson R, Trevena L, van der Weijden T, Witteman HO, Stacey D.   +16 more
europepmc   +1 more source

Patient decision aid-supported shared decision making and short-term decision-making outcomes in type 2 diabetes: a prospective observational comparative study. [PDF]

BMC Med Inform Decis Mak
Hsu SH, Chiang CH, Lin CH, Huang SH, Keller JJ, Wang LH, Tang KP.   +6 more
europepmc   +1 more source

International Patient Decision Aid Standards (IPDAS): beyond decision aids to usual design of patient education materials [PDF]

Health Expectations, 2007
openaire   +2 more sources