Results 71 to 80 of about 730,624 (302)

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

The development of a patient decision aid to reduce decisional conflict about antidepressant use in pregnancy

BMC Medical Informatics and Decision Making, 2022
Background People with moderate to severe depression in pregnancy must weigh potential risks of untreated or incompletely treated depression against the small, but uncertain risks of fetal antidepressant drug exposure.
Neesha Hussain-Shamsy, Sarah Somerton, Donna E. Stewart, Sophie Grigoriadis, Kelly Metcalfe, Tim F. Oberlander, Carrie Schram, Valerie H. Taylor, Cindy-Lee Dennis, Simone N. Vigod   +9 more
doaj   +1 more source

A 'combined framework' approach to developing a patient decision aid: the PANDAs model [PDF]

, 2014
Background There is a lack of practical research frameworks to guide the development of patient decision aids [PtDAs]. This paper described how a PtDA was developed using the International Patient Decision Aids (IPDAS) guideline and UK Medical ...
A Coulter, A Coulter, A Coulter, Alastair Bradley, AM O’connor, B Fishhoff, Brigitte Colwell, C Charles, Chirk Jenn Ng, D Feldman-Stewart, D Feldman-Stewart, D Flynn, F Legare, G Elwyn, G Elwyn, HA Llewellyn-Thomas, HL Bekker, J Paling, JA Adam, JW Creswell, M Campbell, M Marschollek, M Privitera, MA Durand, N Mathers, Nigel Mathers, P Craig, P Slovic, PB Thompson, RJ Volk   +29 more
core   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Developing a patient decision aid for Achilles tendon rupture management: a mixed-methods study

BMJ Open, 2023
Objective To develop and user-test a patient decision aid portraying the benefits and harms of non-surgical management and surgery for Achilles tendon ruptures.Design Mixed methods.Setting A draft decision aid was developed using guidance from a ...
Ian A Harris, Tammy C Hoffmann, Kirsten McCaffery, Christopher G Maher, Rachel Thompson, Sam Adie, Joshua R Zadro, Jan F L Gan, Marnee J McKay, Caitlin M P Jones   +9 more
doaj   +1 more source

Intratumoral heterogeneity analysis reveals hidden associations between protein expression losses and patient survival in clear cell renal cell carcinoma. [PDF]

, 2017
Intratumoral heterogeneity (ITH) is a prominent feature of kidney cancer. It is not known whether it has utility in finding associations between protein expression and clinical parameters. We used ITH that is detected by immunohistochemistry (IHC) to aid
Devarajan, Karthik, Dulaimi, Essel, Jiang, Wei, O\u27Neill, Raymond, Parsons, Theodore, Peiper, Stephen C., Solomides, Charalambos C., Testa, Joseph R., Uzzo, Robert, Wang, Qiong, Yang, Haifeng   +10 more
core   +3 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Making Research Outputs Accessible to People with Kidney Disease: Implementing the Dialysis Decision Aid. [PDF]

, 2016
Purpose: To assess the impact of implementation activities on decision aid use by people making dialysis decisions. The Dialysis Decision Aid booklet was launched by a UK kidney disease charity when the research assessing its acceptability to patients ...
Bekker, HL
core  

Patient Acceptability of the Yorkshire Dialysis Decision Aid (YoDDA) Booklet: A Prospective Non-Randomized Comparison Study Across 6 Predialysis Services [PDF]

, 2016
Background: Patients are satisfied with their kidney care but want more support in making dialysis choices. Predialysis leaflets vary across services, with few being sufficient to enable patients’ informed decision making.
Abhyankar P., Bekker H., Bekker H.L., Conner M., Coulter A., Horne R., Janis I.L., Leventhal A., Ley P., Loud F., Légaré F., National Clinical Guideline Centre – CG125., National Clinical Guideline Centre – CG182., O'Connor A., Ormandy P., Stacey D., Stein A., Tabachnick B.G., Trevena L.J., Von Winterfeldt D.   +19 more
core   +2 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source