Results 91 to 100 of about 19,050,112 (390)

A Systems Thinking Approach to Redesigning the Patient Experience to Reduce 30 Day Hospital Readmission [PDF]

, 2018
INTRODUCTION The cost of medical care is spiraling out of control, and one of the many reasons is lack of preventative care, poor communication to the patient and primary caregiver(s) both in an inpatient and outpatient setting.
DePrince, RN, BA, CCRN, SCRN, Maureen, Flounders, MBA, William, Gates, MBA, Justin, Heffner, MBA, Steven, Lawler, BS, RN, MSN, FNP-BC, MBA, Michael, Pardini, MBA, Julia, Rosenwasser, MD, MBA, FACS, FAHA, Robert H.   +6 more
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Patient Outcomes After Hospital Discharge to Home With Home Health Care vs to a Skilled Nursing Facility.

JAMA Internal Medicine, 2019
Importance Use of postacute care is common and costly in the United States, but there is significant uncertainty about whether the choice of postacute care setting matters.
Rachel M. Werner, Norma B. Coe, Mingyu Qi, R. Konetzka   +3 more
semanticscholar   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Hearing the voices of older adult patients: processes and findings to inform health services research [PDF]

, 2019
Background Clinical academic research and service improvement is planned using Patient and Public Involvement and Engagement (PPIE) but older PPIE participants are consulted less often due to the perception that they are vulnerable or hard to engage.
A Clarke, A Coffey, A Faulkner, A Gregory, A Pratesi, A Rojas-García, A Shankar, AW Ekdahl, C Patmore, C Patmore, Cordis, E Hanson, F Thilo, J Gordon, J Kitzinger, J Mamon, J Sixsmith, KT Fuji, L Locock, L Lévesque, L Meehan, M Minkler, MET McMurdo, MM Ismail, MTE Puts, NF Sheridan, PA Reay, R Stocker, S George, S Slatyer   +29 more
core   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

The Effects of Patient Education and Knowledge of CHF Patients As Evaluated by the PakSAC Survey [PDF]

, 2016
After diagnosis, management of congestive heart failure (CHF) can pose quite a struggle to many patients, since it requires that lifestyle changes be implemented into their daily life.
Tovar, Nabil
core   +2 more sources

Improving patient discharge and reducing hospital readmissions by using Intervention Mapping

BMC Health Services Research, 2014
BackgroundThere is a growing impetus to reorganize the hospital discharge process to reduce avoidable readmissions and costs. The aim of this study was to provide insight into hospital discharge problems and underlying causes, and to give an overview of ...
G. Hesselink, M. Zegers, M. Vernooij-Dassen, P. Barach, C. Kalkman, Maria Flink, Gunnar Ön, Mariann Olsson, S. Bergenbrant, C. Orrego, R. Suñol, Giulio Toccafondi, F. Venneri, Ewa Dudzik-Urbaniak, B. Kutryba, L. Schoonhoven, H. Wollersheim   +16 more
semanticscholar   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source