Results 71 to 80 of about 18,789,759 (342)

Nurses’ functional status assessments using the International Classification of Functioning, Disability, and Health across hospital types in Japan: A cross-sectional study

Belitung Nursing Journal
Background: In Japan, patients receiving treatment in advanced acute care hospitals often cannot return home immediately and require ongoing hospitalization.
Kanako Yamamoto
doaj   +1 more source

Lack of patient involvement in care decisions and not receiving written discharge instructions are associated with unplanned readmissions up to one year

, 2017
This retrospective, cross-sectional study examined the relationship between aspects of inpatient communication and discharge instructions and unplanned, all-cause readmissions using individual-level data up to one-year post-discharge.
Kyle A Kemp, Maria J Santana, Kemp, Kyle A, Santana, Maria J, Maria Santana, Hude Quan, Kyle Kemp, Quan, Hude   +7 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Patient-initiated discharge from emergency departments and the related factors in Jiroft, South of Iran [PDF]

Journal of Holistic Nursing and Midwifery
Introduction: Patients’ self-discharge may indicate dissatisfaction with healthcare services. In some cases, it can lead to re-hospitalization or even the death of the patient.
Shima Groohi-sardou, Akbar Anaei Goudari, Vahid Rahmanian, Reza Faryabi, Najmeh Ghasemian, Ehsan Goroei Sardou, Salman Daneshi   +6 more
doaj  

Patient-reported medication-related problems (MRPs) four weeks post-discharge.

, 2019
Patient-reported medication-related problems (MRPs) four weeks post-discharge.
Fatma Karapinar-Çarkit (6449162), Sara Daliri (6449153), Marie-Christine van Buul-Gast (6449159), Wilma J. M. Scholte op Reimer (6449156), Gerben ter Riet (3639), Bianca M. Buurman (189272), Bart J. F. van den Bemt (4500796), Jacqueline G. Hugtenburg (5792864)   +7 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A scoping review of patient discharge from intensive care: opportunities and tools to improve care.

Chest, 2015
BACKGROUND We conducted a scoping review to systematically review the literature reporting patient discharge from ICUs, identify facilitators and barriers to high-quality care, and describe tools developed to improve care.
H. Stelfox, D. Lane, Jamie M. Boyd, S. Taylor, L. Perrier, S. Straus, D. Zygun, D. Zuege   +7 more
semanticscholar   +1 more source

Virtual Nurse Discharge: Improving Patient and Nurse Experience

This case study reviews the virtual discharge nurse (VDN) process and its impact on patient experience and nursing workflow as an exemplar of an effective telehealth innovation at a community hospital 23-bed Short Stay Unit (SSU).
Wright, Fay, Oates, Carolyn, Davis, Stacey, Flihan, Dina, Odell, Christine   +4 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source