Results 81 to 90 of about 1,375,311 (317)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Impact of Annual Appraisal Processes on Nurses’ Job Performance and Satisfaction: A Systematic Review [PDF]

علوم بهداشتی ایران
Background and Purpose: Nursing performance significantly influences healthcare outcomes. Given the essential role of performance appraisals (PAs) in professional development, this review aims to systematically evaluate the impact of annual appraisals on
Jincy Joseph, Bejoy Varghese
doaj  

Patient-centred learning in practice. A mixed methods study of supervision and learning in student clinics

, 2023
Objective: Patient-centred learning (PCL) allows medical students to practice a patient-centred approach; however, didactic characteristics of PCL have yet to be fully elucidated.
Karl-Johan Schmidt Nielsen, Pia Strand, Strand, Pia, Kjær, Louise Binow,, Nielsen, Karl Johan Schmidt, Nielsen, Karl Johan Schmidt,, Louise Binow Kjær, Christensen, Mette Krogh, Christensen, Mette Krogh,, Strand, Pia,, Mette Krogh Christensen, Lund University., Kjær, Louise Binow   +12 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Beyond technology acceptance—a focused ethnography on the implementation, acceptance and use of new nursing technology in a German hospital

Frontiers in Digital Health
IntroductionHospitalised patients could benefit from the emergence of novel technologies for nursing care. There are numerous technical products available, but these rarely find their way into practice.
Ronny Klawunn, Urs-Vito Albrecht, Deliah Katzmarzyk, Marie-Luise Dierks   +3 more
doaj   +1 more source

Patient autonomy and education in specific medical knowledge [PDF]

The asymmetry between the patient as a layman and the physician as an expert is a key element in health economics. However, a change to a higher degree of patient autonomy has taken place.
Lukas, Daniel
core  

When Is Patient Education Unethical?

, 2008
Although patient education is central to the ethical practice of nursing, it can be practiced in an ethically contested or unethical way. It is sometimes used to: forward a societal goal the individual might not have chosen; assume that patients should ...
Redman, Barbara K.
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

A Survey of Nurses' and Patients' Opinions about Patient Education and Training and Possible Barriers in Madani Cardiovascular Health and Education Center [PDF]

Taṣvīr-i salāmat, 2017
Background and Objectives: Patient education is an effective nursing care to increase patient satisfaction with health care, reduce anxiety and the length of hospitalization and costs.
Afkham Varghaei-Paidar, Vahideh Zareh Gavgani, Nader Hassannejhad, Saeedeh Ranjbar, Marzieh Hosseinzadeh, Shahin Imani   +5 more
doaj  

Patient experience of care in a student-faculty collaborative practice

, 2014
Student Run Clinics (SRCs) are a popular means of caring for the underserved while providing valuable medical education opportunities. Reports of patient experience surveys are rare in this setting.
Laura Huppert, Knudsen, Janine, Elman, Scott, Powe, Camille, Pratyaksh Kumar Srivastava, Huppert, Laura, Barnett, Michael, Kyle Dempsey, Janine Knudsen, Rebecca Berman, Donelan, Karen, Dempsey, Kyle, Srivastava, Pratyaksh Kumar, Scott Elman, Karen Donelan, Camille Powe, Berman, Rebecca A, Rebecca A Berman, Michael Barnett, Pratyaksh Srivastava   +19 more
core   +1 more source