Results 161 to 170 of about 2,063,671 (406)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Management for improving patients’ knowledge and understanding about drug allergy

Pharmacy Practice, 2015
Background: Drug allergy a serious adverse drug reaction commonly concerned in healthcare practice. Inadequate documentation and communication between health providers, and limited health literacy and knowledge in patients could contribute to the re ...
Jarernsiripornkul N, Chaipichit N, Chumworathayi P, Krska J   +3 more
doaj  

Revitalizing Sex Education for Chinese Children: A Formative Study [PDF]

arXiv
Sex education helps children obtain knowledge and awareness of sexuality, and protects them against sexually transmitted diseases, pregnancy, and sexual abuse. Sex education is not well taught to children in China -- both school-based education and parental communication on this topic are limited. To interrogate the status quo of sex education in China
arxiv  

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

A Novel Approach to Scalable and Automatic Topic-Controlled Question Generation in Education [PDF]

arXiv
The development of Automatic Question Generation (QG) models has the potential to significantly improve educational practices by reducing the teacher workload associated with creating educational content. This paper introduces a novel approach to educational question generation that controls the topical focus of questions. The proposed Topic-Controlled
arxiv  

Conversation Starters: Research Insights from Clinicans and Patients on Conversations about End-of-Life Care and Wishes [PDF]

, 2016
The John A. Hartford Foundation, Cambia Health Foundation, and California Health Care Foundation commissioned PerryUndem Research/ Communication to conduct focus groups among health care clinicians and patients on the topic of end-of-life care and wishes.

core  

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

Molecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns, Ulrik Ringborg, Julio Celis, Bengt Jönsson, Michael Baumann   +4 more
wiley   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Oral health education for systemic sclerosis patients: A booklet report

PEC Innovation, 2023
Purpose/objectives: Systemic sclerosis (SSc) is a rare chronic autoimmune disease characterized by vascular abnormalities and connective tissue disorders.
Thalles G. Almeida, Alessandra R.H. Ferreira, Felipe S. da Silva, Caio C. Chaves, Bárbara N. Assunção, Priscila S. Martins, Alessandra S. das Dores, Regina M.F. de Moura, Júnia A. Andrade, Flávia P.S.T. Santos, Gilda A. Ferreira, Débora C. Calderaro   +11 more
doaj  

Promoting AI Competencies for Medical Students: A Scoping Review on Frameworks, Programs, and Tools [PDF]

arXiv
As more clinical workflows continue to be augmented by artificial intelligence (AI), AI literacy among physicians will become a critical requirement for ensuring safe and ethical AI-enabled patient care. Despite the evolving importance of AI in healthcare, the extent to which it has been adopted into traditional and often-overloaded medical curricula ...
arxiv