Results 181 to 190 of about 2,650,202 (337)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Readability assessment of online patient education materials for central centrifugal cicatricial alopecia

International Journal of Women's Dermatology, 2023
Ogechi Ezemma, BA, Deega Omar, MPH, Jessica B. Brown-Korsah, BS, Jazmin Newton, BS, Susan C. Taylor, MD   +4 more
doaj   +1 more source

Arabic version of the patient education materials assessment tool (PEMAT): translation and validation. [PDF]

Saudi Pharm J
Alrasheed MA, Almobarak A, Alfayyadh HM, Alkahtani A, Balkhi B.   +4 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Improving the readability of trauma patient education materials: a ChatGPT solution demonstrated using materials by the Orthopaedic Trauma Association. [PDF]

OTA Int
Covarrubias O, Ghanem D, Murdock C, Domes C, Shafiq B.   +4 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Improving the Readability of Institutional Heart Failure-Related Patient Education Materials Using GPT-4: Observational Study. [PDF]

JMIR Cardio
King RC, Samaan JS, Haquang J, Bharani V, Margolis S, Srinivasan N, Peng Y, Yeo YH, Ghashghaei R.   +8 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Enhancing Patient Education with AI: A Readability Analysis of AI-Generated Versus American Academy of Ophthalmology Online Patient Education Materials. [PDF]

J Clin Med
Kufta AY, Djalilian AR.
europepmc   +1 more source

Patient Education Materials in Dermatology [PDF]

JAMA Dermatology, 2016
Arpan V, Prabhu, Raghav, Gupta, Christopher, Kim, Ahmed, Kashkoush, David R, Hansberry, Nitin, Agarwal, Ellen, Koch   +6 more
openaire   +2 more sources