Results 131 to 140 of about 382,587 (364)

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Patient and Physician Perspectives of Treatment Burden in Multiple Sclerosis

Neurology and Therapy
The number of disease-modifying therapies (DMTs) approved for the treatment of multiple sclerosis (MS) has greatly increased in recent decades, leading to higher treatment complexity.
Barry A. Singer, Dawn Morgan, Julie A. Stamm, Anita A. Williams   +3 more
doaj   +1 more source

Polysubstance Abuse: Alcohol, Opioids and Benzodiazepines Require Coordinated Engagement by Society, Patients, and Physicians [PDF]

, 2015
Uzor C. Ogbu, Shahram Lotfipour, Bharath Chakravarthy   +2 more
openalex   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Measuring the Impact of Humanistic Care: A Six-Item Scale to Enhance Patient Trust

Journal of Patient Experience
UAB Medicine, a leading health system serving over 1.5 million patients annually, conducted a study to identify factors driving trust in primary care and family medicine.
Chris Brainard MSHA, Amber Maraccini PhD, CPXP   +1 more
doaj   +1 more source

Regulatory landscape with U.S. patient requirements and Clinical Trial Diversity expectations

Contemporary Clinical Trials Communications
The Food and Drug Administration (FDA) has an expectation that products filed for marketing authorization have to include data that are representative of the US patient population.
Elizabeth George, Alicia Baker McDowell, Melissa Vozza, Talley Mitchell, Ben Quartley, Cassandra S. Kennedy, Bill Hanlon   +6 more
doaj   +1 more source

Developing a Framework for Evaluating the Patient Engagement, Quality, and Safety of Mobile Health Applications

, 2021
Karandeep Singh, David W. Bates
openalex   +1 more source

How does patient experience fit into the overall healthcare picture?

, 2014
Understanding the experience of patients provides insight into health care as well as being a crucial first step towards partnering with patients to drive improvement.
Luxford, Karen, BSc(Hons), PhD, FAIM, FAAQHC, Sutton, Sue, RN, PhD, FHIMSS   +1 more
core   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source