Results 141 to 150 of about 3,545,202 (343)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Developing and Implementing a Narration of Care Framework to Teach Nurses When and How to Narrate Care

Nursing Reports
Background: It is generally well-known that narration of care is critically important to high-quality nursing care. Narration of care is loosely defined as a nurse’s ability to describe to patients and families the clinical purpose behind nursing ...
Courtenay R. Bruce, Natalie N. Zuniga-Georgy, Nathan Way, Lenis Sosa, Emmanuel Javaluyas, Terrell L. Williams, Gail Vozzella   +6 more
doaj   +1 more source

Improving the patient's experience.

Community eye health, 2008
When arriving at the eye care unit, patients often feel unsure of what is going to happen, anxious, and vulnerable. Many have never found themselves in a hospital setting before or have never travelled or slept away from home.It is an integral part of eye care to make sure a patient's experience is a positive one.
C Patricia Fathers, Sue Stevens
openaire   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

US food allergy patients’ experiences, priorities, and needs: A qualitative study

Journal of Allergy and Clinical Immunology: Global
Background: Understanding patient experiences with food allergies (FAs) is essential for developing treatments that meet patients’ needs and aiding clinicians in optimizing care.
Elisabeth Oehrlein, MS, PhD, Silke C. Schoch, MA, Omar A. Escontrías, DrPH, MPH, Melanie Carver, AS, Sanaz Eftekhari, BA, Jessica Marvel, MPH, Chris Leo Pashos, PhD, Michael Pistiner, MD, MMSc, Randall Rutta, MA, Jill Voss, BSc Hons, MSc, Joe Vandigo, MBA, PhD   +10 more
doaj   +1 more source

Patients Receiving Palliative Care and Their Families' Experiences of Participating in a “Patient-Centered Family Meeting”: A Qualitative Substudy of the Valuing Opinions, Individual Communication, and Experience Feasibility Trial

, 2021
Philippa Cahill, Elizabeth Lobb, Christine Sanderson, Jane Phillips   +3 more
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Patients’ and volunteer coaches’ experiences with an informal social network intervention in forensic psychiatric care: a qualitative analysis [PDF]

, 2023
Lise T. A. Swinkels, Mariken B. de Koning, Thimo M. van der Pol, Jack Dekker, Janna F. ter Harmsel, Arne Popma   +5 more
openalex   +1 more source

Postpartum Patients Reports of Satisfaction with a Welcome Meal after a Vaginal Delivery [PDF]

, 2009
Objective: The purpose of this research study was to assess patient perspectives regarding a special Welcome Meal. The focus was on patients\u27 feeling welcomed and important because prior research has shown that when a patient\u27s expectations are ...
Pinilla, Jessica R.
core   +1 more source