Results 201 to 210 of about 1,888,458 (261)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Geographic Differences in Patient Experience After a Diagnosis of Lobular Breast Cancer. [PDF]

Ann Surg Oncol
Graham-Stephenson A, Fanning CE, Geven EL, Migyanka F, Jeruss JS.   +4 more
europepmc   +1 more source

Anti‐CD20 Discontinuation Versus Continuation in People Aged Over 50 With Non‐Active Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy.
Alexia Moukhine, Fabien Rollot, Romain Casey, Nicolas Collongues, Sandra Vukusic, Guillaume Mathey, Anne Laure Dubessy, Jonathan Ciron, Jérôme De Seze, Aurélie Ruet, Pierre Labauge, Arnaud Kwiatkowski, Hélène Zephir, Caroline Papeix, Gilles Defer, Christine Lebrun‐Frenay, David Axel Laplaud, Eric Berger, Eric Thouvenot, Jean Pelletier, Abdullatif Al Khedr, Olivier Casez, Bertrand Bourre, Abir Wahab, Laurent Magy, Jean‐Philippe Camdessanché, Ines Doghri, Solène Moulin, Mariana Sarov Rivière, Karolina Hankiewicz, Amélie Dos Santos, Corinne Pottier, Eric Manchon, Jennifer Aboab, Maia Tchikviladze, Thomas David, Gilles Edan, Emmanuelle Le Page, Laure Michel, Anne Kerbrat, OFSEP Investigators   +40 more
wiley   +1 more source

Balint Groups as a Workforce and Patient Experience Strategy: Lessons From Implementation. [PDF]

J Patient Exp
Hobbs M, Arrigo M, Mike Boutin ER.
europepmc   +1 more source

Quality, Patient Experience, and Service Gaps in Home Healthcare in Saudi Arabia: A Systematic Review Aligned with Vision 2030. [PDF]

Saudi Med J
Alawad E, Mahrous RM, Elshaib LA.
europepmc   +1 more source

Leveraging Learning Health Systems to Address Racial and Ethnic Disparities in Veteran Patient Experience. [PDF]

J Gen Intern Med
Shannon EM, Wong MS, Moy E, Jones KT, Boris J, Washington DL.   +5 more
europepmc   +1 more source

Patient experience data in formulary decision-making: Payer-reported perceptions and use. [PDF]

J Manag Care Spec Pharm
Kheloussi S, Mazar I, Harrington M, Perfetto EM.   +3 more
europepmc   +1 more source