Results 241 to 250 of about 8,661,270 (305)

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Telemedicine for headache disorders in real-world practice: from patient experience to health system impact. [PDF]

Neurol Sci
Grasso R, Carapelle E, Raunich G, Avolio C.   +3 more
europepmc   +1 more source

Vascular Disease, Non‐Steroidal Anti‐Inflammatory Drugs and Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Clare Wotton, Carol Hermon, Sarah Floud, Gillian Reeves, Isobel Barnes   +4 more
wiley   +1 more source

Patient Experience of Primary Care in One Small Hospital and One Non-Bedded Clinic in a Mountainous Rural Area of Japan. [PDF]

J Gen Fam Med
Ohara N, Koda M, Takechi M, Takemoto K, Hirai M, Kato H, Otsuka Y, Taniguchi SI, Son D.   +8 more
europepmc   +1 more source

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

The Effect of Ambient Artificial Intelligence Documentation on Clinician Workload, Efficiency, and Patient Experience in a Multisite Emergency Department Network. [PDF]

Appl Clin Inform
Kashiouris MG, Miner A, Saleh S, Scripps M, Stanton L, Samuel G, Dibble B.   +6 more
europepmc   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Technological Strategies for the Patient Experience in Emergency Departments: Scoping Review. [PDF]

JMIR Med Inform
Santafé AS, Aranda JM, Beltrán WJ, Guerrero WJ, Guevara Lozano M, Bustos IX.   +5 more
europepmc   +1 more source

Primary Language, Social Determinants of Health, and the Lived Patient Experience After Heart Transplantation: A Comparative Qualitative Study. [PDF]

Clin Transplant
Shah MK, Latif Z, Lemos C, Hertz A, Donald E, Fuselier B, Lindekens J, Vargas F, Rahman A, Latif F, Clerkin KJ, Sayer G, Uriel N, DeFilippis EM.   +13 more
europepmc   +1 more source

Evaluation and adaptation of the Seamless Care Optimizing the Patient Experience Mental Health program. [PDF]

Can Fam Physician
Bolea B, Emam M, Smith J, Pomedli S, Picklyk C, Pariser P, Whitmore C.   +6 more
europepmc   +1 more source