Results 151 to 160 of about 543,181 (304)

Picking your brains: a DSS for neurosurgery

, 1995
This research involves the construction of a decision support system (DSS) to assist clinical managers in costing and contracting in the new internal market for neurosurgery in the UK National Health Service.
Lees, P., Powell, P., Connell, N.A.D., Sutcliffe, C.M.S.   +3 more
core  

Evaluation of Patient Identification Practices by Nurses Working at Saigon ENT Hospital

, 2020
Recently, patient misidentification has been identified as a common error in healthcare systems. Six patient safety recommendations from the World Health Organization (2007) have resulted in research and improvements to increase patient safety.
Ngo, My Thi Phuong
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Is it possible to eliminate patient identification errors in medical imaging?

, 2011
Purpose: The aim of this article is to review a system that validates and documents the process of ensuring the correct patient, correct site and side, and correct procedure (commonly referred to as the 3 C's) within medical imaging.
Scally, Peter, Holmes, Penny, Penny Holmes, Danaher, Luke A., Peter Scally, Howells, Joan, Joan Howells, Luke A. Danaher   +7 more
core   +1 more source

Necrotizing Fasciitis of the Hand: Management with Literature Review

Plastic and Reconstructive Surgery, Global Open
Summary:. This report presents a case of necrotizing fasciitis following a seemingly minor injury sustained from handling a spiny plant. Despite initial primary care by a physician, the patient presented with severe septic shock and necrotizing fasciitis
Sarina Delavari, MD, Ioannis-Fivos Megas, MD, Moritz Billner, MD, Bert Reichert, MD, David Breidung, MD   +4 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Enhanced Information Systems Success Model for Patient Information Assurance

, 2021
The current health information systems have many challenges such as lack of standard user interfaces, data security and privacy issues, inability to uniquely identify patients across multiple hospital information systems, probable misuse of patient data,
Abuonji, Paul, Agola, Joshua, Agunga, Lilian Adhiambo   +2 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Factors influencing patient safety incident reporting in African healthcare organisations: a systematic integrative review

BMC Health Services Research
Background Patient safety incidents, defined as deviations from standard healthcare practices, contribute to significant mortality and financial burdens for healthcare systems globally each year.
Gelana Fekadu, Georgia Tobiano, Rachel Muir, Melaku Tadege Engidaw, Andrea P. Marshall   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source