Results 101 to 110 of about 4,184,982 (314)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Improving the patient experience through provider communication skills building [PDF]
, 2014 The doctor’s interpersonal skills are arguably the most important to clinical outcome and patient experience. A peer-facilitated, communication skills-building course for physicians has been provided twice annually since its inception in 2004. The course
Fasolino, John P., MD +2 more
core +1 more source
Isolation of Pseudomonas cepacia in cystic fibrosis patient
Memorias do Instituto Oswaldo Cruz, 1993 Pulmonary infection on cystic fibrosis (CF) patients are associated with a limited qualitative number of microorganisms. During the colonization process, Staphylococcus aureus usually preceedes Pseudomonas aeruginosa.
Elizabeth de Andrade Marques +4 more
doaj +1 more source
Design and in-vitro testing of a portable patient isolation chamber for bedside aerosol containment and filtration. [PDF]
Build Environ, 2022 Mousavi ES +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Exploring patient satisfaction with interdisciplinary care of complex feeding problems [PDF]
, 2016 Measures of patient satisfaction with health care experiences are recognized as essential in the healthcare market environment. To our knowledge, there are no specific patient experience measures that assess patient and caregiver satisfaction with a ...
Miller, Claire K, PhD +1 more
core +1 more source
Isolation of Oropouche Virus from Febrile Patient, Ecuador
Emerging Infectious Diseases, 2018 We report identification of an Oropouche virus strain in a febrile patient from Ecuador by using metagenomic sequencing and real-time reverse transcription PCR. Virus was isolated from patient serum by using Vero cells. Phylogenetic analysis of the whole-
Emma L. Wise +9 more
doaj +1 more source
A prospective clinical evaluation of a patient isolation hood during the COVID-19 pandemic. [PDF]
Aust Crit Care, 2022 McGain F +6 more
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Escuchame: A Story of Patient Resilience [PDF]
This article is a narrative following a patient\u27s experience through the American Healthcare system. This article is written by a second-year medical student. During this time the individual repeatedly engaged in different specialties of medicine such
Braun, John Paul +1 more
core +1 more source