Results 31 to 40 of about 440,904 (297)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

The Service Directory of Patient Library Made by IFLA (International Federation of Library Associations and Institutions) and Its Enlightenment——The Third Study on IFLA [PDF]

open access: yes, 2011
分析了我国病人图书馆存在的不足之处,在详细解释国际图联《病人图书馆服务指南》的基础上,提出了提高我国病人图书馆服务水平的对策。This paper analyzes some shortages existing in China's patient library,and based on detailed explanation of IFLA's Guidelines for Libraries Serving Hospital Patients,puts forward some ...
卢家利, 苏瑞竹
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A pilot project of Cancer Patient Library in Italy: the results of a customer satisfaction survey and its products [PDF]

open access: yes, 2006
The purpose of this study is to determine the degree of satisfaction of the users of the Cancer Information Point (CIP-LP), section of the Library for Patients (LP) active, since 1998, at the National Cancer Institute of Aviano, Italy.
Tirelli, Umberto   +8 more
core  

Determinants of practice for providing decision coaching to facilitate informed values-based decision-making: protocol for a mixed-methods systematic review

open access: yesBMJ Open, 2023
Introduction Decision coaching is a non-directive approach to support patients to prepare for making health decisions. It is used to facilitate patients’ involvement in informed values-based decision-making and use of evidence-based health information. A
Lindsey Sikora   +11 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Table_2_Blood-Bourne MicroRNA Biomarker Evaluation in Attention-Deficit/Hyperactivity Disorder of Han Chinese Individuals: An Exploratory Study.doc [PDF]

open access: yes, 2018
Background: Attention-deficit/hyperactivity disorder (ADHD) is a highly genetic neurodevelopmental disorder, and its dysregulation of gene expression involves microRNAs (miRNAs).
Sung-Chou Li (19928)   +8 more
core   +1 more source

A Study of the Impact of an Educational Intervention on Nurse Attitudes and Behaviours toward Mobile Device Use in Hospital Settings

open access: yesJournal of the Canadian Health Libraries Association, 2017
Introduction: Mobile applications (apps) provide nurses with evidence-based information at the bedside. Librarians encourage app use by purchasing licenses and promoting their features.
Lori Giles-Smith   +4 more
doaj   +1 more source

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