Results 41 to 50 of about 648,403 (339)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Shared decision-making in Israel: status, barriers, and recommendations

open access: yesIsrael Journal of Health Policy Research, 2012
Shared decision making (SDM) - involving patients in decisions relevant to their health - has been increasingly influential in medical thought and practice around the world.
Miron-Shatz Talya   +4 more
doaj   +1 more source

Young peoples' involvement in welfare service development—Is voice enough?—A thematic synthesis of qualitative studies

open access: yesHealth Expectations, 2022
Background Young people need to be heard and take an active role in developing welfare services. When they are recognized as having skills and expertize, the advantages young people's involvement brings to both themselves and the organizations, are ...
Line Nortvedt   +2 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Discursos sobre la participación activa del paciente en el sistema sanitario [PDF]

open access: yesAposta, 2020
Tanto los profesionales como la ciudadanía demandan una transformación hacia un modelo comunicativo en el ámbito sanitario más orientado al paciente-usuario otorgando al encuentro sanitario un carácter más humano, que situé al paciente como el verdadero ...
Virginia Díaz Gorriti   +3 more
doaj  

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Knowledge and Attitudes Towards Clinical Trial Participation in Oman: A cross-sectional study

open access: yesSultan Qaboos University Medical Journal, 2018
Objectives: Clinical trials are prospective studies on human subjects designed to answer various clinical questions. However, only a limited number of clinical trials have been conducted in Oman.
Hussain Al-Lawati   +5 more
doaj   +1 more source

‘Spending the day with your Family Health Team’: rapid ethnography of a patient-centred quality improvement event

open access: yesBJGP Open, 2020
Background: Primary care practices have started to explore different methods of engaging with patients to advance quality improvement. This approach leverages the strengths of citizen engagement; however, there has been a lack of empirical research to ...
Katie N Dainty, Tara Kiran
doaj   +1 more source

More than cost‐effectiveness? Applying a second‐stage filter to improve policy decision making

open access: yesHealth Expectations, 2021
Background Apart from cost‐effectiveness, considerations like equity and acceptability may affect health‐care priority setting. Preferably, priority setting combines evidence evaluation with an appraisal procedure, to elicit and weigh these ...
Kaying Kan   +6 more
doaj   +1 more source

Monitoring and Evaluation of Patient Engagement in Health Product Research and Development: Co-Creating a Framework for Community Advisory Boards

open access: yesJournal of Patient-Centered Research and Reviews, 2022
Purpose: While patient engagement is becoming more customary in developing health products, its monitoring and evaluation to understand processes and enhance impact are challenging.
Sevgi E. Fruytier   +12 more
doaj   +1 more source

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