Results 181 to 190 of about 465,365 (351)

Prone Positioning in Awake, Nonintubated Patients With COVID-19 Hypoxemic Respiratory Failure [PDF]

, 2020
Alison E. Thompson, Benjamin L. Ranard, Ying Wei, Sanja Jelić   +3 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Motion study on upright patient positioning in walk-through PET: evaluation in a clinical setting. [PDF]

EJNMMI Phys
Aziz R, Muller FM, Withofs N, Maebe J, Dadgar M, Vervenne B, D'Asseler Y, Vanhove C, Vandenberghe S.   +8 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Accuracy of day-to-day patient positioning in ocular proton therapy with a dedicated beamline. [PDF]

PLoS One
Hol M, Spruijt KH, Rodrigues MF, Klaver YLB, Kouwenberg J, Bakker PAC, Luyten GPM, Kiliç E, Beenakker JM, Astreinidou E, Rasch CRN.   +10 more
europepmc   +1 more source

A Novel Patient-Positioning Device for Dynamic CT Myelography. [PDF]

AJNR Am J Neuroradiol, 2023
Callen AL, Wojcik R, Bojanowski M.
europepmc   +1 more source

The remarkable tenacity of user charges : a concise history of the participation, positions, and rationales of Canadian interest groups in the debate over "direct patient participation" in health care financing

, 2014
Morris L. Barer, Vandna Bhatia, Greg L. Stoddart, Robert G. Evans   +3 more
openalex   +1 more source

AORN Position Statement on Managing Distractions and Noise During Perioperative Patient Care [PDF]

, 2020
C Christian, M Gustafson, E Roth, D Wiegmann, A Elbardissi, J Dearani, R Daly, T Sundt, R Feuerbacher, K Funk, D Spight, B Diggs, J Hunter, , A Healey, N Sevdalis, C Vincent, P Papadokos, L Snoots, B Wands, P Papadokos, T Smith, E Darling, B Searles, M Feil, M Willett, O Gillman, E Shin, W Yoong, A Khin, N Ramlal, B Loabile, S Forman, C Jorm, O' Sullivan, G, I Suh, J Chien, M Mukherjee, S Park, D Oleynikov, K Siu, G Campbell, K Arfanis, A Smith, J Pluyter, S Buzink, A Rutkowski, J Jakimowicz, M Persoon, H Broos, J Witjes, A Hendrikx, A Scherpbier, M Grissinger, A Padmakumar, O Cohen, A Churton, J Groves, D Mitchell, P Brennan, A Joseph, R Ulrich, C Oliveira, G Arenas, M Enser, J Moriceau, J Abily, C Clark, K Paunovic, S Cheriyan, H Mowery, D Ruckle, S Ginsberg, E Pantin, J Kraidin, A Solina, S Panjwani, G Yang, M Giv, K Sani, M Alizadeh, A Valinejadi, H Majdabadi, E Kulkarni, Y Abdallah, D Hanseman, D Krishnan, M Peters, P Feczko, K Tsang, B Van Rietbergen, J Arts, P Emans, B Tay, I Prabhu, C Cousin, G Cousin, N Verhaert, N Moyaert   +99 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Impact of patient positioning on hemodynamic assessment: A comparison of supine and upright right heart catheterization. [PDF]

Physiol Rep
Chowdhury MA, Squires J, Systrom DM, Waxman AB.   +3 more
europepmc   +1 more source