Results 111 to 120 of about 3,957,184 (313)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Treatment Preferences in Patients With Hypothyroidism

The Journal of Clinical Endocrinology & Metabolism
Abstract Context Levothyroxine (L-T4) monotherapy is the standard of care for the treatment of hypothyroidism. A minority of L-T4–treated patients remain symptomatic and report better outcomes with combination therapy that contains liothyronine (L-T3) or with desiccated thyroid extract (DTE).
Fabyan Esberard de Lima Beltrão, Giulia Carvalhal, Daniele Carvalhal de Almeida Beltrão, Fabricia Elizabeth de Lima Beltrão, Miriam O Ribeiro, Matthew D Ettleson, Helton Estrela Ramos, Antonio C Bianco   +7 more
openaire   +2 more sources

Predicted treatment preferences for each individual patient.

, 2020
Predicted treatment preferences for each individual patient.
Gyanendra Pokharel (8313924), George Tomlinson (270126), Cynthia H. Seow (8313936), Robert Deardon (8313927), Christopher Ma (2726101), Remo Panaccione (319030), Deborah A. Marshall (8313930), Claire Bombardier (8313933), Gilaad G. Kaplan (124401), Glen S. Hazlewood (8313921)   +9 more
core   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Patient preferences for biologic and biosimilar osteoporosis treatments in colombia

, 2020
Purpose: Teriparatide is used to treat patients with established osteoporosis but is often reserved for patients who have inadequate response to antiresorptive therapy. Biosimilar teriparatide, which is believed to have efficacy and safety similar to the
Hauber B., Tockhorn-Heidenreich A., Boeri M., Fernandez M., Florez S., Leonardi F., Burge R.T., Graham-Clarke P.L.   +7 more
core   +1 more source

A Systematic Review of Patient Preferences, Expectations, and Values for the Management and Treatment of Graves Disease

Patient Preference and Adherence
Yingjie Chen,1,* Zonghao Ren,2,* Xiujuan Zhou,3 Peiyang Gao3 1School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Department of Endocrinology, Hospital of Chengdu ...
Chen Y, Ren Z, Zhou X, Gao P
doaj  

Systematic Review of Studies Using Conjoint Analysis Techniques to Investigate Patients’ Preferences Regarding Osteoarthritis Treatment

Patient Preference and Adherence, 2021
Basem Al-Omari,1 Peter McMeekin,2 Angela Bate2 1College of Medicine and Health Sciences, Khalifa University, Abu Dhabi, United Arab Emirates; 2School of Health and Life Science, University of Northumbria, Newcastle-Upon-Tyne, UKCorrespondence: Basem Al ...
Al-Omari B, McMeekin P, Bate A
doaj  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Patients Prefer Being Offered a Mirror to See Their Cervix and External Genitalia During Well-Exams while Clinician Perceptions May Create Barriers to Offering a Mirror: A Mixed Methods Study in a Primary Care Setting

Women's Health Reports
Objective: Patient-centered care is a core value of both Family Medicine and Obstetrics & Gynecology. We sought to know if patients prefer being offered a mirror to see their cervix and external genitalia during asymptomatic speculum exams (Mirror Pelvic
Luci Olewinski, Stephanie Hartmann, Savannah McKenzie, Shannon Lewis, Grace Saxon, Robert Eric Heidel, Fatima Ahmed   +6 more
doaj   +1 more source