Results 121 to 130 of about 3,957,184 (313)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Understanding patient preferences and willingness to pay for hemophilia therapies

, 2015
Shraddha S Chaugule,1 Joel W Hay,1 Guy Young2 1Department of Clinical Pharmacy, Pharmaceutical Economics and Policy, University of Southern California, 2Hemostasis and Thrombosis Center, Children’s Hospital Los Angeles, University of Southern ...
Chaugule SS, Hay JW, Young G
core  

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Japanese patient preferences regarding intermediate to advanced hepatocellular carcinoma treatments

, 2019
Tetsuhiro Chiba,1 Atsushi Hiraoka,2 Shigeru Mikami,3 Masami Shinozaki,4 Yukio Osaki,5 Masamichi Obu,6 Takamasa Ohki,7 Naoyuki Mita,8 Dianne Ledesma,8 Nariaki Yoshihara,8 Kathleen Beusterien,9 Kaitlan Amos,9 John FP Bridges,10 Osamu Yokosuka111Department ...
Hiraoka A, Amos K, Osaki Y, Ledesma D, Yokosuka O, Mikami S, Obu M, Beusterien K, Bridges JFP, Yoshihara N, Ohki T, Mita N, Chiba T, Shinozaki M   +13 more
core  

Content Refinement and Multicenter Validation of the ELIGES Patient Experience Questionnaire Focused on Nursing Care During Hospitalization: Study Protocol

Nursing Reports
Background: Patient experience has become a key component of healthcare quality assessment and improvement. Although its importance is increasingly recognized, there is a lack of standardized instruments specifically designed to assess patient experience
Noelia Navamuel-Castillo, Josep-Oriol Casanovas-Marsal, Ángel Boned-Galán, Ana Belén Hernández-Ruiz, Nieves López-Ibort, Ana Gascón-Catalán   +5 more
doaj   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Patient preferences and satisfaction in the treatment of rheumatoid arthritis with biologic therapy

, 2009
Jennifer L BartonDivision of Rheumatology, University of California San Francisco, San Francisco, California, USAAbstract: Significant advances in the treatment of rheumatoid arthritis (RA) have been made over the past 10 years with the introduction of ...
Jennifer L Barton
core  

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Shared decision-making in radiotherapy for rectal cancer – A systematic review

Technical Innovations & Patient Support in Radiation Oncology
Background: Shared decision-making (SDM) is increasingly emphasized in the ESMO guidelines for rectal cancer (RC). This review aim to describe the current landscape for SDM for radiotherapy (RT) in RC, investigate patient and clinician preferences ...
Lise Kjær Schou, Anne Wilhøft Kristensen, Johanne Hollands Steffensen, Marianne Grønlie Guren, Laurids Østergaard Poulsen, Karen-Lise Garm Spindler, Camilla Jensenius Skovhus Kronborg   +6 more
doaj   +1 more source