Results 71 to 80 of about 3,957,184 (313)

Patient preferences in the treatment of diabetic retinopathy

, 2011
Barbara Wirostko1, Kathleen Beusterien2, Jessica Grinspan2, Thomas Ciulla3, John Gonder4, Alexandra Barsdorf1, Andreas Pleil51Pfizer, New York, NY, USA; 2Oxford Outcomes, Bethesda, MD, USA; 3Midwest Eye Institute, Indianapolis, IN, USA; 4Ivey Eye ...
Grinspan J, Pleil A, Wirostko B, Barsdorf A, Gonder J, Beusterien K, Ciulla T   +6 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Who should be prioritized for renal transplantation?: Analysis of key stakeholder preferences using discrete choice experiments [PDF]

, 2012
Background Policies for allocating deceased donor kidneys have recently shifted from allocation based on Human Leucocyte Antigen (HLA) tissue matching in the UK and USA. Newer allocation algorithms incorporate waiting time as a primary factor, and in
Clark, M. D., Higgins, R., Moro, Domenico, Anil Gumber, West, N. (Nick), Clark Michael D, Higgins, Robert, Leech Dennis, Nick West, Gumber Anil, Leech, D., Moro, D., Higgins Robert, Gumbar, A., Dennis Leech, Higgins, Rob, Szczepura, Ala; id_orcid, Leech, Dennis, Gumber, Anil, Szczepura, Ala, Michael D Clark, West, Nick, West Nick, Szczepura Ala, Clark, Michael D, Clark, M. D. (Michael D.), West, N., Robert Higgins, Ala Szczepura, Moro Domenico, Domenico Moro   +30 more
core   +2 more sources

A Multinational Study of Patient Preferences for How Decisions Are Made in Their Care

, 2022
Inadequate consideration has been given to patient preferences for patient-centered care (PCC) across countries or cultures in our increasingly global society.
Jones, L, Jones, Liz, Pines, Rachyl, Pamoso, Aron H., Pearson, Annika, Pamoso, AH, Sheeran, N, Pamoso, Aron Harold, Jin, Yin, Benedetti, M, Benedetti, Maria, Pearson, A, Jin, Y, Sheeran, Nicola, Jin, Yin (Blair), Pines, R, Maria Benedetti, Rachyl Pines, Liz Jones, Aron H. Pamoso, Annika Pearson, Yin (Blair) Jin, Nicola Sheeran   +22 more
core   +1 more source

Individual decision making about lung cancer screening: A conjoint analysis of perspectives among a high‐risk national sample

Cancer Medicine, 2019
Objectives Lung cancer screening (LCS) is effective in reducing lung cancer mortality, but there is limited information available regarding preferences among high‐risk individuals concerning LCS.
Margaret M. Byrne, Richard J. Thurer, Jamie L. Studts   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Questionnaire on patient preferences (version Q1).

, 2023
Questionnaire on patient preferences (version Q1).
Suzete Costa (3919679), Céu Mateus (499420), Inês Teixeira (4399561), João Pereira (499421), Dennis K. Helling (13758223), José Guerreiro (13758220)   +5 more
core   +1 more source

Patient Preference Studies for Advanced Prostate Cancer Treatment Along the Medical Product Life Cycle: Systematic Literature Review

Patient Preference and Adherence, 2022
Dominik Menges,1 Michela C Piatti,1 Thomas Cerny,2,3 Milo A Puhan1 1Epidemiology, Biostatistics and Prevention Institute (EBPI), University of Zurich (UZH), Zurich, Switzerland; 2Foundation Board, Cancer Research Switzerland (Krebsforschung Schweiz KFS),
Menges D, Piatti MC, Cerny T, Puhan MA
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

General Practice: Four Empirical Essays on GP Behaviour and Individuals’ Preferences for GPs [PDF]

On June 1, 2001 a reform took place in Norwegian general practice. This implied some advantages of importance to empirical analysis. First, a new organisation and a new payment system were introduced, which makes it possible to perform before-after ...
Lurås, Hilde
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