Results 81 to 90 of about 3,740,894 (266)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Collaborative care in real-world settings: barriers and opportunities for sustainability

open access: yesPatient Preference and Adherence, 2017
Katherine Sanchez1,2 1School of Social Work, The University of Texas at Arlington, Arlington, 2Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA Abstract: Patient-centered care and self-management of chronic ...
Sanchez K
doaj  

Patient Admission Preferences and Perceptions

open access: yesWestern Journal of Emergency Medicine, 2015
Introduction: Understanding patient perceptions and preferences of hospital care is important to improve patients’ hospitalization experiences and satisfaction.
Clayton Wu   +7 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Assessing patient preferences in heart failure using conjoint methodology

open access: yes, 2015
Giovanni Pisa,1 Florian Eichmann,1 Stephan Hupfer21Kantar Health GmbH, Munich, Germany; 2Novartis Pharma GmbH, Nuernberg, GermanyAim: The course of heart failure (HF) is characterized by frequent hospitalizations, a high mortality rate, as well as a ...
Eichmann F, Hupfer S, Pisa G
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Carpal tunnel surgery: patient preferences and predictors for satisfaction

open access: yes, 2012
Grant D Shifflett, Christopher J Dy, Aaron DaluiskiDepartment of Orthopaedic Surgery, Division of Hand and Upper Extremity Surgery, Hospital for Special Surgery, New York, NY, USAAbstract: Carpal tunnel syndrome is a debilitating disease of the upper ...
Daluiski A, Dy CJ, Shifflett GD
core  

Preferences of overweight and obese patients for weight loss programs: a discrete-choice experiment

open access: yesInternational Journal of Integrated Care, 2013
Introduction: Obesity is associated with increased risk of morbidity and mortality and also appears to have an adverse effect on health-related quality of life.
Axel Mühlbacher, Susanne Bethge
doaj  

Myeloma Patient Value Mapping: A Discrete Choice Experiment on Myeloma Treatment Preferences in the UK

open access: yesPatient Preference and Adherence, 2020
Simon Fifer,1 Jayne Galinsky,2 Sarah Richard3 1Community and Patient Preference Research (CaPPRe), Sydney, NSW, Australia; 2Myeloma UK, Edinburgh, Scotland; 3PRMA, Edinburgh, ScotlandCorrespondence: Simon FiferCommunity and Patient Preference Research ...
Fifer S, Galinsky J, Richard S
doaj  

Patient Preferences Regarding Device Reuse and Potential of Devices for Reuse - A Study in a Veteran Population

open access: yesIndian Pacing and Electrophysiology Journal, 2013
Background: Many cardiac patients need and undergo device implants. Veterans’ preferences regarding post-mortem handling of devices are not known. Cardiac patients in low- and middle-income countries who need but cannot afford devices rely on donations ...
Indiresha R. Iyer
doaj   +1 more source

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