Results 91 to 100 of about 2,860,764 (308)

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Establishing meaningful change thresholds for European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire CLL‐specific module domain scores: An analysis based on the TRANSCEND CLL 004 study in patients with relapsed or refractory chronic lymphocytic leukaemia or small lymphocytic lymphoma

eJHaem
Introduction The study aimed to establish meaningful thresholds at patient and group levels for the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire CLL‐specific module (EORTC QLQ‐CLL17) domain scores in adults ...
Laurie Eliason, Fatoumata Fofana, Lin Wang, Peter A. Riedell, Shien Guo   +4 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Relationship Between Quantitative MRI Biomarkers and Patient-Reported Outcome Measures After Cartilage Repair Surgery: A Systematic Review. [PDF]

, 2018
Background:Treatment of articular cartilage injuries remains a clinical challenge, and the optimal tools to monitor and predict clinical outcomes are unclear.
Cole, Brian J, Cotter, Eric, Davey, Annabelle, Lansdown, Drew A, Wang, Kevin   +4 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Report from the fourth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative) [PDF]

, 2016
This article is a report of the fourth meeting of the Harmonising Outcome Measures for Eczema (HOME) initiative held in Malmö, Sweden on 23–24 April 2015 (HOME IV).
Abuabara, K.,, Aoki, V.,, Apfelbacher, C. J.,, Ardeleanu, M.,, Awici-Rasmussen, M.,, Barbarot, S.,, Berents, T. L.,, Bjerring Clemmensen, K. K.,, Block, J.,, Bragg, A.,, Burton, T., Chalmers, J. R.,, Creswell-Melville, A.,, Dinesen, M.,, Drucker, A.,, Eckert, L.,, Flohr, C.,, Garg, M.,, Gerbens, L. A A,, Graff, A. L B,, Hanifin, J.,, Heinl, D.,, Humphreys, R.,, Ishii, H. A.,, Kataoka, Y.,, Leshem, Y. A.,, Lund University., Lund University., Marquort, B., Massuel, M. A.,, Merhand, S.,, Mizutani, H.,, Murota, H.,, Murrell, D. F.,, Nakahara, T.,, Nasr, I., Nograles, K.,, Ohya, Y.,, Osterloh, I.,, Pander, J.,, Prinsen, C.,, Purkins, L.,, Ridd, M.,, Sach, T.,, Schmitt, J.,, Schuttelaar, M. L A,, Shindo, S.,, Simpson, E.,, Singh, J. A.,, Smirnova, J.,, Spuls, P. I.,, Sulzer, A.,, Svensson, Åke,, Synnøve Gjerde, E.,, Takaoka, R.,, Tauber, M.,, Thomas, K. S.,, Torchet, F.,, Vestby Talmo, H.,, Volke, A.,, von Kobyletzki, L.,, Wahlgren, C. F.,, Weidinger, S.,, Weisshaar, E.,, Williams, H. C.,, Wollenberg, A.,, Yamaga, K.,, Zhao, C. Y.,   +67 more
core   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Patient-Reported Outcome of Physical Therapy in Amyotrophic Lateral Sclerosis: Observational Online Study [PDF]

, 2018
Background: Physical therapy is an essential component of multidisciplinary treatment in amyotrophic lateral sclerosis (ALS). However, the meaning of physical therapy beside preservation of muscular strength and functional maintenance is not fully ...
Funke, Andreas, Kettemann, Dagmar, Maier, André, Meyer, Robert, Meyer, Thomas, Münch, Christoph, Spittel, Susanne, Steinfurth, Laura   +7 more
core   +1 more source

Patient reported outcomes [PDF]

European Journal of Cardiovascular Nursing, 2015
Crispin, Jenkinson, David, Morley
openaire   +2 more sources