Results 251 to 260 of about 2,875,336 (355)

Questioning the questionnaire: a Dutch national survey on generic patient-reported outcome measures in traumatology. [PDF]

J Patient Rep Outcomes
Houwen T, van Ditshuizen JC, Havermans RJM, Geuze RE, de Jongh MAC, Verhofstad MHJ.   +5 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Involving Patients in Developing a Patient-Reported Outcome Measure for Retinal Detachment. [PDF]

Ophthalmol Sci
Manning-Charalampidou S, Woudstra-de Jong J, Faridpooya K, Manzulli M, van Romunde S, Geeraert P, Hillier R, van Busschbach J, Vingerling J, Pesudovs K.   +9 more
europepmc   +1 more source

Using patient‐reported outcome measures in clinical trials: perspectives for and against a modular approach

Carrie‐Anne Ng, Jessica Roydhouse, Tim Luckett, Richard De Abreu Lourenço, Brendan Mulhern   +4 more
openalex   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Patient reported outcome measures relevant to asthma remission: scoping review protocol. [PDF]

MethodsX
Michaud A, Politis J, Faktor L, Bardin PG, Chan AH, Leong P.   +5 more
europepmc   +1 more source

Digitization of Patient-Reported Outcomes [PDF]

Value in Health, 2013
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Measurement properties of patient-reported outcome measures for rotator cuff repair surgery. [PDF]

J Shoulder Elbow Surg
Sahoo S, Li Y, Cogan CJ, Entezari V, Ho JC, Iannotti JP, Ricchetti ET, Derwin KA, Lapin B.   +8 more
europepmc   +1 more source