Results 111 to 120 of about 1,479,071 (353)

Reliability, validity, responsiveness, and minimal important change of the Disabilities of the Arm, Shoulder and Hand and Constant-Murley scores in patients with a humeral shaft fracture [PDF]

, 2017
Background: The Disabilities of the Arm, Shoulder and Hand (DASH) and Constant-Murley scores are commonly used instruments. The DASH is patient-reported, and the Constant-Murley combines a clinician-reported and a patient-reported part. For patients with
Hartog, D. (Dennis) den, Lieshout, E.M.M. (Esther) van, Mahabier, K.C. (Kiran), Theyskens, N. (Nina), Verhofstad, M.H.J. (Michiel)   +4 more
core   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Patient-Reported Outcome Measures for Abdominal Aortic Aneurysm: A systematic review and qualitative evidence synthesis [PDF]

, 2016
Background: The aim was to identify and evaluate existing patient reported outcome measures (PROMs) for use in patients with an abdominal aortic aneurysm (AAA) to inform the selection for use in surgical practice.
Benson, Black, Borchard, Brännström, Buscemi, COSMIN, Critical Appraisal Skills Programme (CASP), Dawson, Devlin, Edwards, Farmer, Fitzpatrick, Food, Grant, Jenkinson, Lamping, Letterstål, Liberati, Macefield, Mangione, McKenna, Morris, O'Cathain, Peach, Peach, Peach, Pettersson, Ritchie, Smith, Terwee, Terwee, Terwee, Vardulaki, Waton, Waton   +34 more
core   +2 more sources

OP0251 THE EULAR SYSTEMIC SCLEROSIS IMPACT OF DISEASE (SCLEROID) SCORE – A NEW PATIENT-REPORTED OUTCOME MEASURE FOR PATIENTS WITH SYSTEMIC SCLEROSIS [PDF]

, 2020
Mike Oliver Becker, R. Dobrota, K. Fligelstone, A. Roennow, Yannick Allanore, Patrícia Carreira, L. Czirják, C. Denton, Roger Hesselstrand, Gunnel Sandqvist, Otylia Kowal‐Bielecka, Cosimo Bruni, M. Matucci Cerinic, Carina Mihai, Ana Maria Gheorghiu, Ulf Müller‐Ladner, Joe Sexton, Turid Heiberg, Oliver Distler   +18 more
openalex   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Incorporating development of a patient-reported outcome instrument in a clinical drug development program: examples from a heart failure program. [PDF]

, 2016
BackgroundPatient-reported outcome (PRO) measures can be used to support label claims if they adhere to US Food & Drug Administration guidance. The process of developing a new PRO measure is expensive and time-consuming.
Anatchkova, Milena, Chau, Dina, Malik, Fady I, Oko-Osi, Hafiz, Patrick, Donald L, Spertus, John, Teerlink, John R, von Maltzahn, Robyn, Wiklund, Ingela   +8 more
core   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Patient reported outcomes used in clinical trials and core outcome sets for individuals with genetic intellectual disability: a scoping review

Journal of Neurodevelopmental Disorders
Background The impact of genetic intellectual disability (GID) on daily life is significant. To better understand the impact of GID, it is essential to measure relevant patient reported outcomes (PROs).
Nadia Y. van Silfhout, Maud M. van Muilekom, Clara D. van Karnebeek, Joost G. Daams, Lotte Haverman, Agnies M. van Eeghen   +5 more
doaj   +1 more source

Patient-oriented and performance-based outcomes after knee autologous chondrocyte implantation: a timeline for the first year of recovery [PDF]

, 2014
It is well established that autologous chondrocyte implantation (ACI) can require extended recovery postoperatively; however, little information exists to provide clinicians and patients with a timeline for anticipated function during the first year ...
English, R. A., Howard, J. S., Lattermann, C., Mattacola, C. G., Mullineaux, David   +4 more
core   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source