Results 231 to 240 of about 1,843,947 (302)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Influence of Sociodemographic Factors on Patient Completion of Patient-Reported Outcome Measures in Hand Surgery Patients. [PDF]

J Hand Surg Glob Online
Goodrich E, Smith T, Gudi M, Girma NM, Wilson C, Day CS.   +5 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Cognitive and Patient-Reported Outcome Measures in LGI-1-IgG Autoimmune Encephalitis. [PDF]

Ann Clin Transl Neurol
Ongphichetmetha T, Swetlik C, Thompson N, Aboseif A, Punia V, Lapin B, Cohen JA, Galioto R, Kunchok A.   +8 more
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

The Influence of Aerobic Exercise Therapy on Patient-Reported Outcome Measures Following Concussion: A Scoping Review. [PDF]

Biomedicines
Cordingley DM, Buchwald SCL, Marquez I, Zeiler FA.   +3 more
europepmc   +1 more source

Patient-Reported Outcome Measures After Botulinum Toxin for Temporomandibular-Related Myalgia: A Prospective Study. [PDF]

J Clin Med
van Soest M, Remijn L, Tak I, van der Hoeve E, Koppendraaier L, de Ruiter M.   +5 more
europepmc   +1 more source

Patient-reported outcome measures for use in patients with alpha-1-antitrypsin deficiency: results of a systematic selection process. [PDF]

BMJ Open Respir Res
Müller K, Vogl L, Knüttel H, Greulich T, Lammert F, Strnad P, Vogelmeier CF, Wilkens M, Bals R, Koller M.   +9 more
europepmc   +1 more source

Dialysis Symptom Index: Patient-reported outcome measures study of dialysis patients in low resource settings in India. [PDF]

World J Nephrol
Pichumani A, Kodaganallur Parthasarathi P, Mani N, Damal Kandadai S, Rathakrishnan D, Moka MK, Sundar L, George M.   +7 more
europepmc   +1 more source