Results 221 to 230 of about 10,695,329 (297)

Implementation of patient-reported outcome measures in oncology practice: a communication-centered qualitative study on patient and healthcare professional perspectives. [PDF]

Qual Life Res
He L, Teunissen AEW, Bol N, de Ligt KM, Krahmer E.   +4 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Measurement properties of patient-reported outcome measures for colorectal cancer: a systematic review. [PDF]

Front Oncol
Xu W, Hong Y.
europepmc   +1 more source

Patient Reported Outcome Measurements

Journal of Pharmaceutical Research, 2015
openaire   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Impact of comorbidity on patient reported outcome measures for men with localised prostate cancer. [PDF]

BMC Urol
Parry MG, Bailey AV, Belin TR, Elashoff D, Foster C, Graham I, Kowalski C, Kwan L, Millar J, Sibert NT, Weller S, Wilhalme H, Litwin MS, Moore CM, TrueNTH Global Registry.   +14 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Patient-Reported Outcome Measures After Liver Resection: A Prospective Single-Center Analysis of Patient-Reported Outcomes and Predictors of Recovery. [PDF]

Cancers (Basel)
Colangelo M, Di Martino M, Gatto T, Baroffio P, Donadon M.   +4 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Response to Letter to the Editor: Comment on "Psychometric Performance of Clinician- and Patient-Reported Outcome Measures in Surgically Treated Thoracic Myelopathy: A Multicenter Prospective Study". [PDF]

Global Spine J
Kato S, Kawamura N, Yamato Y, Iizuka Y, Takigawa T, Hongo M, Takami M, Takahashi S, Takahashi J, Fukui M, Sekiguchi M, Ikegami S, Hashizume H, Chikuda H, Watanabe K, Kanchiku T, Kanayama M, Ito Y.   +17 more
europepmc   +1 more source