Results 61 to 70 of about 1,030,601 (304)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Clinical evaluation of knee joint diseases

Journal of Joint Surgery and Research, 2023
Purpose: This article aimed to comprehensively introduce clinical scoring of pathological conditions of the knee. Methods: Review articles on the clinical scores of knee joints were searched. The frequency of the clinical scores used in said articles are
Kohei Nishitani, Shinichiro Nakamura, Shinichi Kuriyama   +2 more
doaj  

Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review

Journal of Medical Internet Research, 2020
Background Medication adherence is essential for improving the health outcomes of patients. Various patient-reported outcome measures (PROMs) have been developed to measure medication adherence in patients.
Y. Kwan, S. Weng, D. H. F. Loh, J. K. Phang, Livia Jia Yi Oo, Dan V. Blalock, Eng-Hui Chew, K. Z. Yap, C. Tan, Sungwon Yoon, W. Fong, Truls Østbye, L. Low, H. Bosworth, J. Thumboo   +14 more
semanticscholar   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

The future of measuring patient‐reported outcomes in rheumatology: Patient‐Reported Outcomes Measurement Information System (PROMIS) [PDF]

Arthritis Care & Research, 2011
The National Institutes of Health (NIH) Patient-Reported Outcomes Measurement Information System (PROMIS®) Roadmap initiative (www.nihpromis.org) is a cooperative research program designed to develop, evaluate, and standardize item banks to measure patient-reported outcomes (PROs) across different medical conditions as well as the US population (1 ...
Khanna, Dinesh, Krishnan, Eswar, Dewitt, Esi Morgan, Khanna, Puja P., Spiegel, Brennan M. R., Hays, Ron D.   +5 more
openaire   +3 more sources

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Completeness of repeated patient-reported outcome measures in adult rehabilitation: a randomized controlled trial in a diverse clinical population

BMC Health Services Research
Background Data collection through patient-reported outcome measures (PROMs) is essential for the purpose of rehabilitation research and registries. Existing problems with incomplete PROM data may relate to the patient burden and data set length.
Anne-Lene Sand-Svartrud, Ingvild Kjeken, Renate Foss Skardal, Gunhild M. Gjerset, Tonje Jossie Johnsen, Anne Dorte Lyken, Hanne Dagfinrud, Rikke Helene Moe   +7 more
doaj   +1 more source

Concurrent Validity and Reliability of the Transfer Assessment Instrument Questionnaire as a Self-Assessment Measure

Archives of Rehabilitation Research and Clinical Translation, 2020
Objectives: To evaluate the psychometric properties of the Transfer Assessment Instrument Questionnaire (TAI-Q), a self-assessment measure to evaluate transfer quality compared with clinician-reported measures.
Lynn A. Worobey, PhD, DPT, ATP, Stephanie K. Rigot, DPT, Michael L. Boninger, MD, Randall Huzinec, PT, Jong H. Sung, PhD, ATC, Kaitlin DiGiovine, Laura A. Rice, PhD, MPT, ATP   +6 more
doaj  

Patient-Reported Outcome Measures in Urethral Reconstruction [PDF]

Current Urology Reports, 2018
Treatment of anterior urethral stricture disease (USD) has shifted from endoscopic approaches to urethroplasty with significantly higher success rates among reconstructive urologists. This academic stance has led to a critical evaluation of "success" and developing disease-specific instruments to assess surgical outcomes focusing on patients ...
Baradaran, Nima, Hampson, Lindsay A, Edwards, Todd C, Voelzke, Bryan B, Breyer, Benjamin N   +4 more
openaire   +4 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source