Results 91 to 100 of about 16,816,868 (338)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

AStudy of the Importance of Issues of Patients’ Bill of Rights from the Viewpoint of Health Care Recipients in Education and Treatment Centers of Qom University of Medical Sciences, 2013, Iran

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2014
Background and Objectives: An Efficient health care systemrequires active participation and appropriate interaction between recipients and providers of health services.
Ameneh Seyed Farajollah   +3 more
doaj  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Medical Students’ Awareness of Patients’ Rights in Qom University of Medical Sciences and Health Services (2010) [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2012
Introduction: Patient rights include the duties that medical team has towards him and the total privileges, abilities or special permissions granted to patients by law.
Seyed Ahmad Bathaei, Hamid Asayesh
doaj  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

The Observance of Patient Rights in the Emergency Departments of Hospitals in Golestan Province, Iran [PDF]

open access: yesنشریه پرستاری ایران
Background & Aims Observance of patients’ rights by nurses is very important for patient satisfaction and the improvement of their health. This study aimed to determine and compare the level of the observance of patients’ rights by nurses from the ...
Asieh Soleimani   +2 more
doaj  

Assessment of Admission to Discharge Process in Order to Improve the Patient Satisfaction in Noornegat Private Hospital in Tabriz, 2014 [PDF]

open access: yesTaṣvīr-i salāmat, 2016
Background and Objectives : The assessment of patient satisfaction in health care and also enhancing the quality of the hospital without paying attention to the needs, expectations and satisfaction of the patients is impossible.
Ali janati   +3 more
doaj  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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