Results 51 to 60 of about 5,862,677 (310)

An Analysis of The Attitude of Patients Towards Using Their Patient Rights at A University Hospital

Florence Nightingale Journal of Nursing, 2019
Aim: This study has been performed descriptively in order to determine the attitudes of patients towards their own rights mentioned in the “Patients’ Rights Act” that is in effect.
Ayten ZAYBAK, İsmet EŞER, Elif GÜNAY İSMAİLOĞLU   +2 more
doaj  

Life, death, and 280 characters: a hashtag analysis of #AssistedSuicide on X (2015–2025)

Frontiers in Digital Health
BackgroundPopulation aging and the growing prevalence of chronic diseases pose significant challenges to the global healthcare system and highlight the relevance of issues related to the end-of-life stages.
Elisa Opriessnig, Olena Litvinova, Olena Litvinova, Zilin Ma, Yining Hua, Yining Hua, Yining Hua, ArunSundar MohanaSundaram, Maria Kletecka-Pulker, Maria Kletecka-Pulker, Maria Kletecka-Pulker, Atanas G. Atanasov, Atanas G. Atanasov, Atanas G. Atanasov, Atanas G. Atanasov, Thomas Wochele-Thoma   +15 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

A Bill of "Rights" for patients with COPD: the "right" therapy for the "right" patient at the "right" time [PDF]

Thorax, 2009
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality and poses significant burdens on patients, their families and the healthcare system. It is currently the fourth leading cause of death in the USA and is projected to rank fifth in burden of disease globally by 2020.1 Pulmonary rehabilitation (PR) for COPD is an ...
openaire   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Genomic Sequencing Capacity, Data Retention, and Personal Access to Raw Data in Europe

Frontiers in Genetics, 2020
Whole genome/exome sequencing (WGS/WES) has become widely adopted in research and, more recently, in clinical settings. Many hope that the information obtained from the interpretation of these data will have medical benefits for patients and—in some ...
Shaman Narayanasamy, Varvara Markina, Adrian Thorogood, Adriana Blazkova, Adriana Blazkova, Mahsa Shabani, Bartha M. Knoppers, Barbara Prainsack, Barbara Prainsack, Robert Koesters   +9 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Developing patient-centred care: an ethnographic study of patient perceptions and influence on quality improvement. [PDF]

, 2015
BACKGROUND: Understanding quality improvement from a patient perspective is important for delivering patient-centred care. Yet the ways patients define quality improvement remains unexplored with patients often excluded from improvement work.
Cicely Marston, Marston, Cicely, Renedo, Alicia, Alicia Renedo   +3 more
core   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source