Results 111 to 120 of about 2,405,537 (303)
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Patient Safety, 2019 Falls are a common and often devastating health threat for hospitalized patients, as they can cause serious injuries such as a hip fracture, and even lead to death.1 Falls in Pennsylvania continue to be one of the biggest contributors to patient harm and
Susan C. Wallace, Caitlyn Allen
doaj +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Patient Safety Alert: Serious Harm Associated With Failure to Adjust Clozapine Dosing
Patient Safety, 2023 Patient Safety Authority
doaj +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Understanding Healthcare Disparities in Pennsylvania: We Need Your Help
Patient Safety, 2023 Patient Safety Authority
doaj +1 more source
Health Courts: An Alternative for Resolving Medical Liability Claims [PDF]
, 2006 Summarizes "'Health Courts' and Accountability for Patient Safety," a report describing a model for administrative compensation featuring health courts as an alternative to the tort system.
Lauren Necochea
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