Results 201 to 210 of about 1,511,209 (259)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Optimizing Patient Selection for Reduced Nonrelapse Mortality After Reduced-Intensity Conditioning: A CIBMTR Analysis. [PDF]

Transplant Cell Ther
Akahoshi Y, Bejanyan N, Nakasone H, Kusuda M, Tada Y, Sakaida E, Atsuta Y, Kanda Y, Fukuda T.   +8 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Impact of RAPID-Based Patient Selection on Endovascular Therapy Outcomes in Acute Ischemic Stroke: A Retrospective Comparative Study. [PDF]

J Neuroendovasc Ther
Kamogawa N, Inoue M, Yakushiji Y, Fujimoto S, Ihara M, Koga M, Sakai N.   +6 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Liver transplantation for hepatocellular carcinoma: from patient selection and downstaging to risk stratification and post-transplant surveillance. [PDF]

Gastroenterol Rep (Oxf)
Rezaee-Zavareh MS, Yang JD.
europepmc   +1 more source

Impact of Publicly Reported Outcomes on Patient Selection for Hematopoietic Cell Transplantation. [PDF]

JCO Oncol Pract
Strouse C, Juckett M, Logan BR, Estrada-Merly N, Peterson A, Preussler JM, Truong TH, Troy JD, Khera N, Wood WA, Rangarajan HG, Akard LP, Bhatt NS, Sharma A, Rizzo JD, Saber W.   +15 more
europepmc   +1 more source

The Role of Local and General Anaesthesia in Modern Dental Practice: Clinical Decision-Making Frameworks, Patient Selection, Trends, Challenges, and Outcomes. [PDF]

Cureus
Anand V, Nareshkumar SS, Maakhni E, Shrivastava KP, Arora V, Mathur J.   +5 more
europepmc   +1 more source

Cardiac contractility modulation in heart failure management: unraveling molecular mechanisms to improve patient selection in heart failure management. [PDF]

Heart Fail Rev
Verelst FR, Van Assche L, Heggermont W, Trenson S, Huybrechts W, Heidbuchel H, Gevaert AB, Van Craenenbroeck EM.   +7 more
europepmc   +1 more source