Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
Co-Constructive Patient Simulation as an Experiential Tool for Continuing Professional Development in Healthcare. [PDF]
de Carvalho Filho MA +2 more
europepmc +1 more source
Multiple Patient Simulation Tests Different Milestones Than Single Patient Simulation
Thomas S. Barker +2 more
semanticscholar +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Automated capture and transfer of human facial expressions to humanoid robots for realistic patient simulation. [PDF]
Schwarz P +5 more
europepmc +1 more source
Platform system to create biofabricated 3D spinal cord tissue models: Combining high resolution PCL fiber placement, a customized, hyaluronic acid‐based hydrogel, two cell types (spinal cord neurons and astrocytes) together with three distinct laminin isoforms allow the formation of functional cell–cell network interactions.
Nicoletta Murenu +12 more
wiley +1 more source
Adolescent-Parent Dyad and Adolescent Eating Disorders: A Standardized Patient Simulation. [PDF]
Gao C +5 more
europepmc +1 more source
Teaching nursing management of diabetic ketoacidosis: a description of the development of a virtual patient simulation. [PDF]
Mahou F +6 more
europepmc +1 more source
Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia
This paper introduces a platform based on magnetic artificial cilia for providing controllable dynamic mechanical stimulation to single cells, suitable for investigating large cell populations and enabling live cell imaging. Proof‐of‐principle experiments show that cell morphology is strongly influenced by the artificial cilia, that cellular forces can
Roel Kooi +5 more
wiley +1 more source
Virtual patient simulation to enhance medical students' clinical communication and decision-making skills: a pilot study. [PDF]
Dávidovics A +4 more
europepmc +1 more source

