Results 271 to 280 of about 27,806,140 (362)

Efficacy of Contractility Modulation Therapy in Patients with Transthyretin Amyloid Cardiomyopathy, Mildly Reduced to Reduced EF and NYHA III and IV: A Multicentric, Prospective Pilot Study for AMY-CCM Registry

Procolo Marchese, Francesca Gennaro, Giovanni Mazzotta, Pierfrancesco Grossi, L Cocchiara, Stefano Guarracini, L Mazzocchetti, Matteo Ziacchi, Mauro Biffi, R Magnano, Massimo Di Marco, Matteo Ruzzolini, Antonio Bisignani, Matteo Bianco, Paolo Garrone, Walter Grosso Marra, Margherita Cannillo, Carlo Lavalle, Daniele Masarone, Cristina Chimenti   +19 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Geometric Microstructural Characteristics of White Matter Differentiate Patients With Facial Dyskinesias and Palsy. [PDF]

CNS Neurosci Ther
Zhu H, Yang A, Luan J, Xu M, Liu B, Lv K, Hu P, Shmuel A, Zhu H, Yuan Z, Shu N, Cheng J, Ma G.   +12 more
europepmc   +1 more source

Risk factors and outcomes for steroid-refractory immune-related hepatotoxicity in locally advanced and metastatic cancer. [PDF]

Cancer Immunol Immunother
Liu S, Zhang Y, Guan Y, Xie H, Dong Y, Chang J, Xie Q, Wang B, Wang J.   +8 more
europepmc   +1 more source