Results 251 to 260 of about 23,688,524 (343)

A Patient with Myeloperoxidase Antineutrophil Cytoplasmic Antibody-Positive Polyangiitis Who Developed Sensorineural Hearing Loss and Scleritis

, 2011
Takafumi Okura, Ken‐ichi Miyoshi, Masanori Jotoku, Daijiro Enomoto, Jun Irita, Tomoaki Nagao, Ryoji Ito, Jitsuo Higaki   +7 more
openalex   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Clinicogenomic and Histopathologic Analyses of Supermassive Intrahepatic Cholangiocarcinoma and the Role of Ablative Radiotherapy. [PDF]

Clin Cancer Res
Abi Jaoude J, Lau A, Yuan Y, Meimoun NS, De B, Liao K, Kouzy R, Nieves-Jimenez HR, Poenisch F, Balter PA, Brock KK, Sawakuchi GO, Vauthey JN, Tzeng CD, Shamsutdinova D, Lazar AJ, Chatterjee D, Holliday EB, Smith GL, Minsky BD, Das P, Koong AC, Lee SS, Tran Cao HS, Javle M, Kwong L, Koay EJ, Ludmir EB.   +27 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Real-World Efficacy and Safety of Tofacitinib for Patients With Alopecia Areata: A Retrospective Multi-Center Cohort Study. [PDF]

Clin Transl Sci
Jin Y, Cao J, Yang S, Liu Y, Tang R, Zeng Y, Huang C, Luo Y.   +7 more
europepmc   +1 more source

The perception of art among patients and staff on a renal dialysis unit

, 2017
C Corrigan, Laura J. Peterson, Clare McVeigh, Peter Lavin, Melotte, G.J., Catherine Wall, A Baker Kerrigan, LAURA PRESTON BARNES, Desmond O’Neill, Hilary Moss   +9 more
openalex   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Multidimensional Measurements of Dysarthria in Myotonic Dystrophy Type 1. [PDF]

Int J Lang Commun Disord
Hellemond SV, Voet N, Kroon R, Sahin Y, Karnebeek I, Nijkamp M, Knuijt S.   +6 more
europepmc   +1 more source

Evaluation of Helicobacter pylori antigen positivity in stool samples of patients with dyspeptic complaints in a tertiary care hospital

, 2013
GATA Haydarpaşa Eğitim Hastanesi, Tıbbi Mikrobiyoloji Servisi, İstanbul, Türkiye, Mehmet Burak Selek   +1 more
openalex   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source