Results 231 to 240 of about 23,688,524 (343)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Chronic diseases: 2010–2011 progress of the unit for chronic patients and evidence-based medicine of Donostia Hospital/Patologías crónicas: evolución 2010–2011 de la unidad de crónicos y medicina basada en la evidencia del Hospital Donostia

International Journal of Integrated Care, 2012
Joxe Artetxe, Kepa Aranegi, Mª Isabel Huertas, Jose Emparanza, Iñaki Dorronsoro, Elena Suquía   +5 more
doaj   +3 more sources

Use of Z-Scores and Percentages to Assess Structural Brain MRI Findings in Patients With Schizophrenia. [PDF]

Int J Methods Psychiatr Res
Mitkani CA, Prassopoulos P, Aletras AH, Fountoulakis KN.   +3 more
europepmc   +1 more source

Mental Health Self-Assessment in Patients With Moderate to Severe Psoriasis: An Observational, Multicenter Study of 1164 Patients in Spain (The VACAP Study)

, 2013
Ramón M. Pujol, L. Puig, E. Daudén, J.L. Sánchez‐Carazo, J. Toribio, F. Vanaclocha, Mireia Yébenes, E. Sabater, Miguel Ángel Casado, M.T. Caloto, Belén Aragón   +10 more
openalex   +1 more source

Safety of stress testing in patients with elevated cardiac biomarkers: Are all modalities created equal? [PDF]

, 2016
Rami Doukky, Yasmeen Golzar
openalex   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Endovascular management of tandem occlusions: current evidence and future directions. [PDF]

J Neurointerv Surg
Krothapalli N, Heit JJ, de Havenon A, Singhal AB, Sussman E, Hasan D, Mac Grory B.   +6 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions. [PDF]

Pharmacol Res Perspect
Hosseini SA, Valadbeigi H, Khoshnazar SM, Khoshnood S, Falahi S, Rezaee D, Hematian A, Haddadi MH.   +7 more
europepmc   +1 more source

Efficacy of Topical Cyclosporine in Mild Dry Eye Patients Having Refractive Surgery [PDF]

, 2014
Kun Wook Kang, Hong Kyun Kim
openalex   +1 more source