Results 111 to 120 of about 154 (153)

Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases

open access: yesComprehensive Physiology, Volume 16, Issue 4, August 2026.
Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal   +2 more
wiley   +1 more source

Phylogeography of the Grassland Skipper Ochlodes venatus Supports the Hypothesis That This Japanese Grassland Insect Has a Long History

open access: yesEcology and Evolution, Volume 16, Issue 8, August 2026.
The key finding of this manuscript is that Ochlodes venatus, a species of Japanese grassland butterfly, inhabited Japan far earlier than previously known. This study estimates O. venatus was distributed in Japan at least 200,000 years ago. This provides crucial evidence that grassland organisms inhabited Japan much earlier than previously thought ...
Naoyuki Nakahama   +6 more
wiley   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

open access: yesJournal of Applied Toxicology, Volume 46, Issue 8, Page 2599-2622, August 2026.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza   +2 more
wiley   +1 more source

Exploring Genetic Therapies Targeting Amyotrophic Lateral Sclerosis in Animal Models: A Systematic Review and Meta‐Analysis

open access: yesThe Journal of Gene Medicine, Volume 28, Issue 8, August 2026.
Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease for which there is currently no known cure. This systematic review explores the efficacy of genetic therapies used to target ALS in preclinical studies using in vivo rodent models. Outcomes investigated include the total number of motor neurons, rodent survival, and muscle function
Hannah E. Wedgwood   +2 more
wiley   +1 more source

Early‐Onset Prostate Cancer: Epidemiology, Risk Factors, Biology, Clinical Features, Management, and Early Detection

open access: yesMedComm, Volume 7, Issue 8, August 2026.
EOPC is a distinct clinicopathological entity separable from SOPC, differing fundamentally in genetic susceptibility, TMPRSS2:ERG fusion frequency, and survival outcomes. Although research remains nascent, this review provides the first comprehensive synthesis of current evidence, offering a critical foundation to guide future investigations into this ...
Xingyu Xiong   +8 more
wiley   +1 more source

When wolves aren't enough: revisiting trophic cascades in northern Wisconsin

open access: yesOikos, Volume 2026, Issue 8, August 2026.
Elimination of top predators has allowed large herbivores to flourish in many terrestrial ecosystems, transforming food webs and ecosystem functions. Restoration of large predator communities is hoped to reverse negative effects of this trophic downgrading, but evidence for such effects is elusive.
Elaine M. Brice   +6 more
wiley   +1 more source

Being wronged and being right: Meaningful Indigenous‐Māori discourses for enhancing environmental restoration

open access: yesPeople and Nature, Volume 8, Issue 8, Page 2781-2795, August 2026.
Abstract Indigenous participation in environmental management is essential for achieving just and effective ecological outcomes. This study investigates the positive discourses that support the integration of Te Ao Māori (the Māori world view) in environmental restoration practice in Aotearoa New Zealand. We introduce Kaupapa Māori Discourse Analysis—a
Kiri Dell, Joanne Clapcott, Kaya Tapu
wiley   +1 more source

Engineering the substrate scope of the thermostable phenolic acid decarboxylase N31 towards sterically hindered phenolic acids

open access: yesProtein Science, Volume 35, Issue 8, August 2026.
Abstract Phenolic acid decarboxylases (PADs) convert bio‐based hydroxycinnamic acids into valuable hydroxystyrene monomers under mild reaction conditions. These compounds are in high demand in polymer production, cosmetics, and flavoring. Especially 4‐vinyl syringol, the decarboxylation product from sinapic acid, generates polymers with similar thermal
Kristin K. F. Bauer   +10 more
wiley   +1 more source

Testing optimal defense theory: Root resistance selection in chicory (Cichorium intybus) reduces foliar defense and alters aphid performance and feeding behavior

open access: yesPest Management Science, Volume 82, Issue 8, Page 7951-7960, August 2026.
Root‐focused resistance in chicory reduces defenses in leaves, impairing root aphids but enhancing foliar aphid performance. Selecting root resistance can create unintended trade‐offs across plant organs. Abstract BACKGROUND Plants are constantly exposed to a wide range of herbivores at both aboveground (AG) and belowground (BG) levels, involving ...
Thomas Cochenille   +5 more
wiley   +1 more source

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

open access: yesAllergy, Volume 81, Issue 8, Page 2582-2632, August 2026.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
Torsten Zuberbier   +221 more
wiley   +1 more source

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