Results 81 to 90 of about 549,106 (324)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Using homological duality in consecutive pattern avoidance [PDF]

open access: yes, 2010
Using the approach suggested in [arXiv:1002.2761] we present below a sufficient condition guaranteeing that two collections of patterns of permutations have the same exponential generating functions for the number of permutations avoiding elements of ...
Khoroshkin, Anton, Shapiro, Boris
core   +1 more source

Optimization with Pattern-Avoiding Input

open access: yesProceedings of the 56th Annual ACM Symposium on Theory of Computing
Permutation pattern-avoidance is a central concept of both enumerative and extremal combinatorics. In this paper we study the effect of permutation pattern-avoidance on the complexity of optimization problems. In the context of the dynamic optimality conjecture (Sleator, Tarjan, STOC 1983), Chalermsook, Goswami, Kozma, Mehlhorn, and Saranurak (FOCS ...
Benjamin Aram Berendsohn   +2 more
openaire   +2 more sources

Pattern avoidance in permutations and their squares [PDF]

open access: yesDiscrete Mathematics, 2019
10 ...
Miklós Bóna, Rebecca Smith 0001
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Generating trees and pattern avoidance in alternating permutations [PDF]

open access: yes, 2010
We extend earlier work of the same author to enumerate alternating permutations avoiding the permutation pattern 2143. We use a generating tree approach to construct a recursive bijection between the set A_{2n}(2143) of alternating permutations of length
Lewis, Joel Brewster
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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