Results 101 to 110 of about 549,106 (324)
On pattern avoiding alternating permutations
European Journal of Combinatorics, 2014 21 pages, 2 ...
Joanna N. Chen +2 more
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Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Pattern Avoidance and the Fundamental Bijection
The Electronic Journal of CombinatoricsThe fundamental bijection is a bijection $\theta:\mathcal{S}_n\to\mathcal{S}_n$ in which one uses the standard cycle form of one permutation to obtain another permutation in one-line form. In this paper, we enumerate the set of permutations $\pi\in\mathcal{S}_n$ that avoids a pattern $\sigma\in\mathcal{S}_3$, whose image $\theta(\pi)$ also avoids ...
Kassie Archer, Robert P. Laudone
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Classical and consecutive pattern avoidance in rooted forests
, 2020 Following Anders and Archer, we say that an unordered rooted labeled forest avoids the pattern $\sigma\in\mathcal{S}_k$ if in each tree, each sequence of labels along the shortest path from the root to a vertex does not contain a subsequence with the ...
Garg, Swapnil, Peng, Alan
core
The 1-box pattern on pattern avoiding permutations
J. Integer Seq., 2013 This paper is continuation of the study of the 1-box pattern in permutations introduced by the authors in \cite{kitrem4}. We derive a two-variable generating function for the distribution of this pattern on 132-avoiding permutations, and then study some of its coefficients providing a link to the Fibonacci numbers.
Kitaev, Sergey, Remmel, Jeffrey
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Patterns in Random Permutations Avoiding the Pattern 132 [PDF]
Combinatorics, Probability and Computing, 2016 We consider a random permutation drawn from the set of 132-avoiding permutations of lengthnand show that the number of occurrences of another pattern σ has a limit distribution, after scaling bynλ(σ)/2, where λ(σ) is the length of σ plus the number of descents.
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source