Results 131 to 140 of about 4,361,783 (305)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Local feature‐based video captioning with multiple classifier and CARU‐attention

IET Image Processing
Video captioning aims to identify multiple objects and their behaviours in a video event and generate captions for the current scene. This task aims to generate a detailed description of the current video in real‐time using natural language, which ...
Sio‐Kei Im, Ka‐Hou Chan
doaj   +1 more source

Pattern classification based on the amygdala does not predict an individual's response to emotional stimuli. [PDF]

Hum Brain Mapp, 2023
Varkevisser T, Geuze E, van den Boom MA, Kouwer K, van Honk J, van Lutterveld R.   +5 more
europepmc   +1 more source

ON THE PATTERN CLASSIFICATION BY LEARNING [PDF]

Bulletin of Mathematical Statistics, 1971
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Feature learning via partial differential equation with applications to face recognition

, 2017
Feature learning is a critical step in pattern recognition, such as image classification. However, most of the existing methods cannot extract features that are discriminative and at the same time invariant under some transforms.
Fang, Cong, Zhao, Zhenyu, Lin, Zhouchen, Zhou, Pan, Pan Zhou, Zhouchen Lin, Zhenyu Zhao, Cong Fang   +7 more
core   +1 more source

A new statistical model for binge drinking pattern classification in college-student populations. [PDF]

Front Psychol, 2023
André J, Diouf M, Martinetti MP, Ortelli O, Gierski F, Fürst F, Pierrefiche O, Naassila M.   +7 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A noise-robust adaptive hybrid pattern for texture classification

, 2014
© 2014 IEEE. In this paper, we focus on developing a novel noise-robust LBP-based texture feature extraction scheme for texture classification. Specifically, two solutions have been proposed to overcome the primary two reasons that cause local binary ...
Jiang, X, Xiubao Jiang, You, F, Xinge You, Ziqi Zhu, Tao, D, Zou, J, Jixing Zou, You, X, Dacheng Tao, Chent, CLP, Zhu, Z, C. L. Philip Chen, Fanyu You   +13 more
core   +1 more source

Revisiting the flexion-valgus type unicondylar posterolateral tibial plateau depression fracture pattern: classification and treatment. [PDF]

J Orthop Surg Res, 2023
Zhu B, Chen J, Zhang Y, Song L, Fang J.
europepmc   +1 more source