Results 201 to 210 of about 4,090,602 (302)

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Genetically predicted dietary diversity protects against renal failure while extreme carbohydrate restriction increases the risk in a Mendelian randomization study. [PDF]

Medicine (Baltimore)
Liang T, Zhang F, Yang F.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Impact of Habitat Changes on Butterfly Diversity in the Forest-Grassland Ecotone in the Source of the Bailong River, Western China. [PDF]

Insects
Zhao M, Bai L, Xia Y, He J, Li X.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Gut Microbiota and Dietary Intake Across Training Phases in Competitive Long-Distance Runners: An Exploratory Longitudinal Study. [PDF]

Nutrients
Kuo CY, Chiu WC, Chou TY, Hsu YJ.
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

The first annotated checklist of the bees of Colombia reveals an overlooked diversity and areas with major data deficiencies. [PDF]

PeerJ
Martín-Rojas RD, Guevara DA, Maldonado Cepeda JD, Gutiérrez Rubiano ND, Vélez D, Gonzalez VH, Ospina-Torres R, Cobb NS, Aguilar-Benavides ML, Almeida EAB, Álvarez Romero J, Arenas-Herrera MJ, Benavides-Lopez JL, Bonilla-Gómez MA, Canal NA, Carrejo NS, Celis CJ, Dorado-Suarez JC, Fagua G, García-Cárdenas DR, García-Moya VA, Guevara-Plata D, Fernández F, Gómez-P LM, Guerrero RJ, Manzano MR, Herrera-Manrique JD, Marín MA, Navas-S GR, Neita Moreno JC, Ramírez SR, Gallego Ropero MC, Restrepo-Rúa M, Sánchez-Alvarán LF, Sardi-Saavedra A, Sarria-Rodríguez V, Sepúlveda Cano PA, Soto-Correa Á, Torres Pineda ED, Torres-Toro J, Vásquez-Lenis EA, Vélez Naranjo MC, Vergara-Navarro EV, Wolff M, Guzman LM, López-Uribe MM.   +45 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source