Results 61 to 70 of about 300,248 (233)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
With the ever-increasing demand for higher data rates and longer talk times, designing low-power RF front ends in wideband code division multiple access (WCDMA) mobile handsets is an important task. However, the power efficiency of current WCDMA RF front ends, particularly power amplifiers, is very low over the range of typical output power levels ...
J.H. Lee, A.B. Raju, R.M. Buehrer
openaire +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Analysis and suggestion of future 5G directions
Firstly,the global research progress of 5G was briefly introduced,and the requirements and challenges of 5G were analyzed.The understanding and views on 5G were shared,and 5G was pointed out as an internet of things generation,a telecom IT generation ...
Shanzhi CHEN
doaj +2 more sources
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
This study investigates a dynamic switching method for signal relay protocols in Cooperative Pattern Division Multiple Access (Co-PDMA) networks. The proposed approach aims to fully utilize the advantages of signal relays in fading-prone environment ...
Wanwei Tang +3 more
doaj +1 more source
Research on Attack Construction and Intrusion Detection Methods for TDMA Wireless Sensor Networks [PDF]
The open nature of wireless media poses a challenge for information security. The Time Division Multiple Access (TDMA) protocol is a predominant protocol tailored for time-sensitive industrial applications.
WEN Minchu, LIANG Wei, ZHANG Jialin
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

