Results 171 to 180 of about 330,129 (233)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

CD138 expression in the endometrium associates with endometrial timing and inflammatory status but not microbiota composition. [PDF]

Hum Reprod
Odendaal J, Fishwick K, Correia GDS, Lee YS, Makwana K, Black N, Southcombe J, Thornton J, Larsen K, Hussain Q, Hawkes A, Kandiyil A, Muter J, Brighton PJ, Vrljicak P, Lucas E, Granne I, Bouliotis G, Bennett PR, Brosens J, MacIntyre DA, Quenby S.   +21 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

3D imaging reveals robustness and plasticity of cell division in rice early embryogenesis. [PDF]

Plant Cell Physiol
Tezuka M, Kitta T, Kumakura H, Sato M, Kamamoto N, Naramoto S, Tsuji H, Okamoto T, Kinoshita A.   +8 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Experimental Assessment of Trigger-Based MU-OFDMA for Deterministic Wi-Fi 6 Operation on COTS Devices. [PDF]

Sensors (Basel)
Orozco-Santos F, Sempere-Payá V, Silvestre-Blanes J.   +2 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Selective Cytogenetic Responses to Nano-Fertilizer Co-Exposure in <i>Allium cepa</i> L.: Implications for Sublethal Phytotoxicity in Agroecosystems. [PDF]

J Xenobiot
Torres-Bugarín O, Sánchez-González A, Ramos-Ibarra ML, Castañeda-Yslas IY, Bogdanchikova N, Pestryakov A, Arellano-García ME.   +6 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Rapid growth of a long-standing dermal nodule in a young Black man: Clinical correlation in an ALK-rearranged epithelioid/spindle cell tumor. [PDF]

JAAD Case Rep
Chang J, Durgin JS, Davis MJ, Breglio KF, Pedersen EA.   +4 more
europepmc   +1 more source