Results 111 to 120 of about 292,760 (265)

Increasing population growth by asymmetric segregation of a limiting resource during cell division

open access: yes, 2013
We report that when budding yeast are transferred to low‐metal environment, they adopt a proliferation pattern in which division is restricted to the subpopulation of mother cells which were born in rich conditions, before the shift.
Nurit Avraham   +3 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Hybrid generalized non-orthogonal multiple access for the 5G wireless networks. [PDF]

open access: yes, 2018
Master of Science in Computer Engineering. University of KwaZulu-Natal. Durban, 2018.The deployment of 5G networks will lead to an increase in capacity, spectral efficiency, low latency and massive connectivity for wireless networks.
Zitha, Samson Manyani.
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

PIC Detector for Piano Chords

open access: yesEURASIP Journal on Advances in Signal Processing, 2010
In this paper, a piano chords detector based on parallel interference cancellation (PIC) is presented. The proposed system makes use of the novel idea of modeling a segment of music as a third generation mobile communications signal, specifically, as a ...
Barbancho AnaM   +2 more
doaj  

Enhanced Spatial Division Multiple Access BCI Performance via Incorporating MEG With EEG

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering
Spatial division multiple access (SDMA) is a way of encoding BCI systems based on spatial distribution of brain signal characteristics. However, SDMA-BCI based on EEG had poor system performance limited by spatial resolution.
Dengpei Ji   +7 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Anatomical variations of renal arteries in adult cadavers in Andhra Pradesh: A multicentric cross-sectional cadaveric study.

open access: yesStudent's Journal of Health Research Africa
Background Anatomical variations in renal artery morphology hold crucial significance in surgical, urological, and radiological procedures. Comprehensive knowledge of these variations enhances the success of renal transplantation, angiography, and ...
Dr. Pratyusha Challa   +3 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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