Results 191 to 200 of about 330,129 (233)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

From Belief to Behavior: Closing the Knowledge-Practice Gap in Irritable Bowel Syndrome Self-management. [PDF]

J Neurogastroenterol Motil
Kim JW.
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Optimal Dietary Patterns for Lower Weight Gain and Risk of Obesity Surrounding Menopause.

JAMA Netw Open
Xia T, Haslam DE, Eliassen AH, Manson JE, Sun Q, Willett WC, Bhupathiraju SN, Zhang C, Hu FB.   +8 more
europepmc   +1 more source

Landscape Characteristics and Distribution of Suitable Habitats for the Black-Tailed Godwit During the Non-Breeding Season: A Case Study of the Middle and Lower Yangtze River Region. [PDF]

Animals (Basel)
Jiang Z, Shao M.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Mixed Papilloma of the Lacrimal Sac as a Cause of Hemolacria. [PDF]

Case Rep Otolaryngol
Malesky C, Falcone M, Hegde P, Falcone TE.   +3 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A novel approach for the EEG-driven assessment of divided attention through mutual information theory: A case study at the wheel. [PDF]

PLoS One
Ronca V, Capotorto R, Giorgi A, Dello Iacono F, Cecchetti M, Napoletano L, Brambati F, Borghini G, Aricò P, Di Flumeri G.   +9 more
europepmc   +1 more source

Branching out: New "out of the seed" hypothesis explains increased specialization of young genes during seed maturation. [PDF]

Plant Cell
Robinson J.
europepmc   +1 more source