Results 101 to 110 of about 3,507,733 (289)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Large-Scale Flow Structure in Turbulent Poiseuille Flows at Low-Reynolds Numbers

Journal of Fluid Science and Technology, 2012
Direct numerical simulations of a spectral method are performed to study the turbulent channel flow at the low-Reynolds numbers, where the quasi-laminar and turbulent regions simultaneously appear and form the stripe pattern, which is floated downstream ...
Koji FUKUDOME, Oaki IIDA
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Pattern formation and selection in quasi-static fracture

, 2000
Fracture in quasi-statically driven systems is studied by means of a discrete spring-block model. Developed from close comparison with desiccation experiments, it describes crack formation induced by friction on a substrate.
A. Groisman, A. T. Skjeltorp, B. Lawn, J. S. Langer, J. T. Neal, J. V. Andersen, J. V. Andersen, J. W. Hutchinson, J. Walker, K. M. Crosby, K.-t. Leung, Kwan-tai Leung, M. Kachanov, P. S. Stevens, S. Boettcher, S. Kitsunezaki, T. Hornig, Y. Bréchet, Zoltan Néda   +18 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Entropy Production in Reaction–Diffusion Systems Confined in Narrow Channels

Entropy
This work analyzes the effect of wall geometry when a reaction–diffusion system is confined to a narrow channel. In particular, we study the entropy production density in the reversible Gray–Scott system.
Guillermo Chacón-Acosta, Mayra Núñez-López   +1 more
doaj   +1 more source

Pattern Formation over Multigraphs

IEEE Transactions on Network Science and Engineering, 2018
Two of the most common pattern formation mechanisms are Turing-patterning in reaction-diffusion systems and lateral inhibition of neighboring cells. In this paper, we introduce a broad dynamical model of interconnected modules to study the emergence of patterns, with the above mentioned two mechanisms as special cases.
Andras Gyorgy, Murat Arcak
openaire   +4 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Taxis-Driven Pattern Formation in Tri-Trophic Food Chain Model with Omnivory

Mathematics
The spatiotemporal dynamics of a three-component model of a food web are considered. The model describes the interactions between populations of resources, prey, and predators that consume both species.
Evgeniya Giricheva
doaj   +1 more source