Results 91 to 100 of about 7,139,942 (297)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Verification of elastically supported beam model for growth mechanism analysis of rail corrugation

open access: yesNihon Kikai Gakkai ronbunshu, 2020
Rail corrugation that causes the vibration and the noise is a phenomenon in which roughness patterns of approximately regular wavelengths are formed on the rail running surface by trains running.
Mitsuo ABOSHI, Hirofumi TANAKA
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Dewetting-mediated pattern formation inside the coffee ring

open access: yes, 2017
The rearrangement of particles in the final stage of droplet evaporation has been investigated by utilizing differential interference contrast microscopy and the formation mechanism of a network pattern inside a coffee ring has been revealed.
蓝鼎   +3 more
core   +1 more source

Constructal theory of pattern formation [PDF]

open access: yesHydrology and Earth System Sciences, 2007
This review article shows that the occurrence of macroscopic flow configuration is a universal natural phenomenon that can be explained and predicted on the basis of a principle of physics (the constructal law): "For a flow system to persist in time
A. Bejan
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Pattern Formation with Trapped Ions

open access: yesPhysical Review Letters, 2011
4 pages ...
Lee, Tony E., Cross, M. C.
openaire   +5 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Textile Transfer Pattern

open access: yes, 1934
Envelope for a McCall Kaumagraph Transfer pattern to make appliqué tulip flower and flower pot designs for suggested items such as kitchen curtains, table runners and pot holders; includes illustrations of finished pieces and instructions for ...
McCall Pattern Company
core  

Editorial: Modeling of cardiovascular systems

open access: yesFrontiers in Physiology, 2022
Yong Wang   +6 more
doaj   +1 more source

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