Results 131 to 140 of about 1,415,133 (306)
Distinct mechanisms underlie pattern formation in the skin and skin appendages
Patterns form with the break of homogeneity and lead to the emergence of new structure or arrangement. There are different physiological and pathological mechanisms that lead to the formation of patterns.
Chuong, CM +24 more
core +1 more source
Defect interactions in the non-reciprocal Cahn–Hilliard model
We present a computational study of the pairwise interactions between defects in the recently introduced non-reciprocal Cahn–Hilliard model. The evolution of a defect pair exhibits dependence upon their corresponding topological charges, initial ...
Navdeep Rana, Ramin Golestanian
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Gene expression time delays & Turing pattern formation systems
The incorporation of time delays can greatly affect the behaviour of partial differential equations and dynamical systems. In addition, there is evidence that time delays in gene expression due to transcription and translation play an important role in ...
Gaffney, Eamonn +5 more
core +1 more source
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
PARAMETRIC DESIGN OF 3D PRINTED RIBBED SLAB SYSTEM BASED ON NATURE-INSPIRED PATTERNS
The interest in pattern geometry and its application to architecture may be seen throughout history. While some authors were fascinated by pattern aesthetics, others were focused on their effectiveness and underlying principles of pattern formation.
Maša Žujović, Jelena Milošević
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

